Evidence map›Paper›PMID 28820691›Full record

ArticleThe American journal of tropical medicine and hygiene2017

Field Trial of the CareStart Biosensor Analyzer for the Determination of Glucose-6-Phosphate Dehydrogenase Activity in Haiti.

Thomas A Weppelmann, Michael E von Fricken, Tara D Wilfong, Elisa Aguenza, Taina T Philippe, Bernard A Okech

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
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  12. Tafenoquine and G6PD: a primer for clinicians.Journal of travel medicine · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Thomas A WeppelmannHerbert Wertheim College of Medicine, Florida International University, Miami, Florida.
Michael E von FrickenDepartment of Global and Community Health, George Mason University, Fairfax, Virginia.
Tara D WilfongEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
Elisa AguenzaDepartment of Global and Community Health, George Mason University, Fairfax, Virginia.
Taina T PhilippeChristianville Foundation Clinic, Gressier, Haiti.
Bernard A OkechEmerging Pathogens Institute, University of Florida, Gainesville, Florida.
George Mason University · USFlorida International University · USUniversity of Florida · USUniversity of Florida Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Throughout many developing and tropical countries around the world, malaria remains a significant threat to human health. One barrier to malaria elimination is the ability to safely administer primaquine chemotherapy for the radical cure of malaria infections in populations with a high prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency. In the current study, a field trial of the world's first quantitative, point-of-care assay for measuring G6PD activity was conducted in Haiti. The performance of the CareStart Biosensor Analyzer was compared with the gold standard spectrophotometric assay and genotyping of the

Indexed as

Biosensing TechniquesAllelesAntimalarialsChildFemaleGenotypeGlucosephosphate DehydrogenaseHaitiHumansMalariaMalePoint-of-Care SystemsPrimaquineAntimalarialsGlucosephosphate DehydrogenasePrimaquine

Identifiers

PMID28820691
PMCPMC5637584
OpenAlexW2749887661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.