Evidence map›Paper›PMID 28820684›Full record

ArticleThe American journal of tropical medicine and hygiene2017

Lack of Efficacy of Liposomal Amphotericin B Against Acute and Chronic

Karl V Clemons, Raymond A Sobel, Marife Martinez, Rodrigo Correa-Oliveira, David A Stevens

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Nanomedicines against Chagas disease: a critical review.Beilstein journal of nanotechnology · 2024
    Review
  3. Review
  4. Review on Experimental Treatment Strategies AgainstJournal of experimental pharmacology · 2021
    Review
  5. Article
  6. Article
  7. Disruption of Intracellular Calcium Homeostasis as a Therapeutic Target AgainstFrontiers in cellular and infection microbiology · 2020
    Review
  8. Vismione B Interferes withThe American journal of tropical medicine and hygiene · 2019
    Article
  9. A Combination of Itraconazole and Amiodarone Is Highly Effective againstThe American journal of tropical medicine and hygiene · 2019
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karl V ClemonsDepartment of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, California.
Raymond A SobelDepartment of Pathology, Veterans Administration Medical Center, Palo Alto, California.
Marife MartinezCalifornia Institute for Medical Research, San Jose, California.
Rodrigo Correa-OliveiraCentro de Pesquisas René Rachou, Fiocruz, Belo Horizonte, Brazil.
David A StevensDepartment of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute and chronic infection with

Indexed as

Trypanosoma cruziAcute DiseaseAmphotericin BAnimalsAntiprotozoal AgentsChagas DiseaseChronic DiseaseDose-Response Relationship, DrugEnzyme-Linked Immunosorbent AssayFemaleMiceMice, Inbred BALB CTreatment FailureAmphotericin BAntiprotozoal Agentsliposomal amphotericin B

Identifiers

PMID28820684
PMCPMC5637596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.