Evidence map›Paper›PMID 28820481›Full record

ReviewToxins2017

Studies on the Presence of Mycotoxins in Biological Samples: An Overview.

Laura Escrivá, Guillermina Font, Lara Manyes, Houda Berrada

Abstract readReview
In one paragraph

Review in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Characterization and toxicological potential ofFrontiers in microbiology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. [The One Health approach in the context of global commodity chains, crises, and food and feed safety].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2023
    Review
  17. Article
  18. Traditional and emergingAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura EscriváLaboratory of Food Chemistry and Toxicology, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain. laura.escriva@uv.es.
Guillermina FontLaboratory of Food Chemistry and Toxicology, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain. guillermina.font@uv.es.
Lara ManyesLaboratory of Food Chemistry and Toxicology, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain. lara.manyes@uv.es.
Houda BerradaLaboratory of Food Chemistry and Toxicology, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain. houda.berrada@uv.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycotoxins are fungal secondary metabolites with bioaccumulation levels leading to their carry-over into animal fluids, organs, and tissues. As a consequence, mycotoxin determination in biological samples from humans and animals has been reported worldwide. Since most mycotoxins show toxic effects at low concentrations and considering the extremely low levels present in biological samples, the application of reliable detection methods is required. This review summarizes the information regarding the studies involving mycotoxin determination in biological samples over the last 10 years. Relevant data on extraction methodology, detection techniques, sample size, limits of detection, and quantitation are presented herein. Briefly, liquid-liquid extraction followed by LC-MS/MS determination was the most common technique. The most analyzed mycotoxin was ochratoxin A, followed by zearalenone and deoxynivalenol-including their metabolites, enniatins, fumonisins, aflatoxins, T-2 and HT-2 toxins. Moreover, the studies were classified by their purpose, mainly focused on the development of analytical methodologies, mycotoxin biomonitoring, and exposure assessment. The study of tissue distribution, bioaccumulation, carry-over, persistence and transference of mycotoxins, as well as, toxicokinetics and ADME (absorption, distribution, metabolism and excretion) were other proposed goals for biological sample analysis. Finally, an overview of risk assessment was discussed.

Indexed as

AflatoxinsAnimalsChromatography, High Pressure LiquidChromatography, LiquidFumonisinsHumansMycotoxinsOchratoxinsSpectrometry, Mass, Electrospray IonizationT-2 ToxinTandem Mass SpectrometryTrichothecenesZearalenoneAflatoxinsdeoxynivalenolFumonisinsHT-2 toxinMycotoxinsochratoxin AOchratoxinsT-2 ToxinTrichothecenesZearalenonebioaccumulationbiological sampleschromatography-mass spectrometrydeterminationextractionmycotoxins

Identifiers

PMID28820481
PMCPMC5577585

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.