Trial reportNutrients2017
Resveratrol in Hepatitis C Patients Treated with Pegylated-Interferon-α-2b and Ribavirin Reduces Sleep Disturbance.
Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07487623 (Evaluation of the Hepatoprotective Effects of a Nutritional Supplement Containing Resveratrol, Quercetin, Taurine, Inulin, and Whey Protein on Biochemical, Molecular, and Clinical Markers in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Hepatoprotective Effects of a Nutritional Supplement Containing Resveratrol, Quercetin, Taurine, Inulin, and Whey Protein on Biochemical, Molecular, and Clinical Markers in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study).
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Effects of resveratrol supplementation on renal function in adults: a systematic review and dose-response meta-analysis.Naunyn-Schmiedeberg's archives of pharmacology · 2025Pooled it
- A Systematic Review of the Impact of Resveratrol on Viral Hepatitis and Chronic Viral Hepatitis-related Hepatocellular Carcinoma.Current molecular medicine · 2025Pooled it
- Potential of Polyphenols for Improving Sleep: A Preliminary Results from Review of Human Clinical Trials and Mechanistic Insights.Nutrients · 2023Pooled it
- Resveratrol in Patients with Minimal Hepatic Encephalopathy.Nutrients · 2018Trial
- Peg-IFNα reduces clinical severity but cannot prevent COVID-19 infection in chronic hepatitis B patients: a cohort study in China.Frontiers in medicine · 2026Article
- Skeletal muscle abnormalities negatively linked to sleep disturbances in patients with liver cirrhosis: a cross-sectional study.European journal of medical research · 2025Article
- Randomized controlled effect of treadmill walking exercise on liver enzymes, psychological burden, and erectile dysfunction in men with hepatitis C.Przeglad gastroenterologiczny · 2024Article
- Dietary polyphenols and sleep modulation: Current evidence and perspectives.Sleep medicine reviews · 2023Review
- Resveratrol and Sir2 Reverse Sleep and Memory Defects Induced by Amyloid Precursor Protein.Neuroscience bulletin · 2023Article
- Research on Mechanisms of Chinese Medicines in Prevention and Treatment of Postoperative Adhesion.Chinese journal of integrative medicine · 2023Review
- Effects of polyphenol-rich interventions on sleep disorders: A systematic review and meta-analysis.Current research in food science · 2023Review
- Resveratrol's neural protective effects for the injured embryoid body and cerebral organoid.BMC pharmacology & toxicology · 2022Article
- Lack of direct association between viral hepatitis and sleep disturbances.Frontiers in medicine · 2022Article
- Therapeutic Applications of Resveratrol in Hepatic Encephalopathy through Its Regulation of the Microbiota, Brain Edema, and Inflammation.Journal of clinical medicine · 2021Review
- Comprehensive Overview of Sleep Disorders in Patients with Chronic Liver Disease.Brain sciences · 2021Review
- The Critical Role of SIRT1 in Parkinson's Disease: Mechanism and Therapeutic Considerations.Aging and disease · 2020Review
- Sleep disorder in patients with chronic liver disease: a narrative review.Journal of thoracic disease · 2020Review
- Frailty and Sleep Disorder in Chronic Liver Diseases.Life (Basel, Switzerland) · 2020Article
- Resveratrol reduces inflammation-related Prostate Fibrosis.International journal of medical sciences · 2020Article
- Influence of Resveratrol on the Immune Response.Nutrients · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatitis C virus infection and interferon treatment have shown to be risk factors for sleep disorder health-related quality of life.
aimTo determine whether the effects of resveratrol on sleep disorders were associated with different tests in subjects with chronic hepatitis C treated with Peg-IFN-α and RBV. PATIENTS AND
methodsIn this prospective, randomized, placebo controlled, double blind clinical trial, 30 subjects (Group A) with chronic hepatitis received Pegylated-Interferon-α2b (1.5 mg/kg per week), Ribavirin and placebo (
resultsThe comparison between Group A and Group B showed significant differences after six months in C-reactive protein (
conclusionsSupplementation with Resveratrol decreased General Health Questionnaire score and reduced sleep disorders in patients treated with Peg-IFN-α and RBV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.