Evidence map›Paper›PMID 28820273›Full record

ArticleAIDS care2018

Psychological distress, health and treatment-related factors among individuals initiating ART in Oromia, Ethiopia.

Angela M Parcesepe, Olga Tymejczyk, Robert Remien, Tsigereda Gadisa, Sarah Gorrell Kulkarni, Susie Hoffman, Zenebe Melaku, Batya Elul, Denis Nash

Abstract read
In one paragraph

Article in AIDS care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Neurocognitive Complications of HIV Infection in Low-Income Countries.Current topics in behavioral neurosciences · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Angela M Parcesepea HIV Center for Clinical and Behavioral Studies , Columbia University and New York State Psychiatric Institute , New York , NY , USA.
Olga Tymejczykb Institute for Implementation Science in Population Health , City University of New York , New York , NY , USA.
Robert Remiena HIV Center for Clinical and Behavioral Studies , Columbia University and New York State Psychiatric Institute , New York , NY , USA.
Tsigereda Gadisad ICAP, Columbia University , New York , NY , USA.
Sarah Gorrell Kulkarnib Institute for Implementation Science in Population Health , City University of New York , New York , NY , USA.
Susie Hoffmana HIV Center for Clinical and Behavioral Studies , Columbia University and New York State Psychiatric Institute , New York , NY , USA.
Zenebe Melakud ICAP, Columbia University , New York , NY , USA.
Batya Elule Department of Epidemiology , Columbia University , New York , NY , USA.
Denis Nashb Institute for Implementation Science in Population Health , City University of New York , New York , NY , USA.
Columbia University · USCity University of New York · USNew York Psychoanalytic Society and Institute · US

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
INSPIRE : Interdisciplinary Social and Behavioral Science Prevention and Intervention REsearch in HIVT32MH019139 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Claude Ann Mellins, Jae M. Sevelius · 1989 to 2026
$10.8M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Multi-level determinants of late ART initiation in sub-Saharan AfricaR01MH089831 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ELUL, BATYA ORIT · 2010 to 2014
$3.6M
NICHD NIH HHS P2C HD050924NIMH NIH HHS P30 MH043520NIMH NIH HHS R01 MH089831NIMH NIH HHS T32 MH019139
6 · The paper itself

Abstract

HIV diagnosis may be a source of psychological distress. Late initiation of antiretroviral therapy (ART) and treatment-related beliefs may intensify psychological distress among those recently diagnosed. This analysis describes the prevalence of psychological distress among people living with HIV (PLWH) and examines the association of recent HIV diagnosis, late ART initiation and treatment-related beliefs with psychological distress. The sample includes 1175 PLWH aged 18 or older initiating ART at six HIV clinics in Ethiopia. Psychological distress was assessed with Kessler Psychological Distress Scale. Scores ≥ 29 were categorized as severe psychological distress. Individuals who received their first HIV diagnosis in the past 90 days were categorized as recently diagnosed. Multivariable logistic regression modeled the association of recent diagnosis, late ART initiation and treatment-related beliefs on severe psychological distress, controlling for age, sex, education, area of residence, relationship status, and health facility. Among respondents, 29.5% reported severe psychological distress, 46.6% were recently diagnosed and 31.0% initiated ART late. In multivariable models, relative to those who did not initiate ART late and had longer time since diagnosis, odds of severe psychological distress was significantly greater among those with recent diagnosis and late ART initiation (adjusted OR [aOR]: 1.9 [95% CI 1.4, 2.8]). Treatment-related beliefs were not associated with severe psychological distress in multivariable models. Severe psychological distress was highly prevalent, particularly among those who were recently diagnosed and initiated ART late. Greater understanding of the relationship between psychological distress, recent diagnosis, and late ART initiation can inform interventions to reduce psychological distress among this population. Mental health screening and interventions should be incorporated into routine HIV clinical care from diagnosis through treatment.

Indexed as

Mental HealthAdolescentAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCross-Sectional StudiesEthiopiaFemaleHIV InfectionsHumansLogistic ModelsMaleMiddle AgedPrevalenceStress, PsychologicalTime FactorsAnti-HIV AgentsARTdiagnosisEthiopiaHIVmental healthtreatment

Identifiers

PMID28820273
PMCPMC5771890
OpenAlexW2748951341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.