Evidence map›Paper›PMID 28820151›Full record

SynthesisIndian journal of ophthalmology2017

A literature review and update on the incidence and microbiology spectrum of postcataract surgery endophthalmitis over past two decades in India.

Prajna Lalitha, Sabyasachi Sengupta, Ravilla D Ravindran, Savitri Sharma, Joveeta Joseph, Vikas Ambiya, Taraprasad Das

Abstract readSystematic Review
In one paragraph

Synthesis in Indian journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Article
  3. Long-term outcomes and factors associated with visual recovery after small-gauge vitrectomy for infectious endophthalmitis: a 10-year experience at a single tertiary center in Taiwan.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Antibiotic susceptibility in Endophthalmitis Management Study and intravitreal antibiotic practice trend in India-EMS Report #5.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  8. Article
  9. Article
  10. Cluster outbreak ofIndian journal of ophthalmology · 2022
    Article
  11. Article
  12. Review
  13. Endophthalmitis - A risk not worth taking.Indian journal of ophthalmology · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prajna LalithaDepartment of Microbiology Laboratory, Aravind Eye Hospital, Madurai, Tamil Nadu, India.
Sabyasachi SenguptaRetina Service, Aravind Eye Hospital, Puducherry, India.
Ravilla D RavindranDepartment of Cataract, Aravind Eye Hospital, Madurai, Tamil Nadu, India.
Savitri SharmaJhaveri Microbiology Laboratory, Hyderabad, Telangana, India.
Joveeta JosephJhaveri Microbiology Laboratory, Hyderabad, Telangana, India.
Vikas AmbiyaSrimati Kanuri Shantamma Retina Vitreous service, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Taraprasad DasSrimati Kanuri Shantamma Retina Vitreous service, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to review the incidence and microbiology of acute postcataract surgery endophthalmitis in India.

methodsSystematic review of English-language PubMed referenced articles on endophthalmitis in India published in the past 21 years (January 1992-December 2012), and retrospective chart review of 2 major eye care facilities in India in the past 5 years (January 2010-December 2014) were done. The incidence data were collected from articles that described "in-house" endophthalmitis and the microbiology data were collected from all articles. Both incidence and microbiological data of endophthalmitis were collected from two large eye care facilities. Case reports were excluded, except for the articles on cluster infection.

resultsSix of 99 published articles reported the incidence of "in-house" acute postcataract surgery endophthalmitis, 8 articles reported the microbiology spectrum, and 11 articles described cluster infection. The clinical endophthalmitis incidence was between 0.04% and 0.15%. In two large eye care facilities, the clinical endophthalmitis incidence was 0.08% and 0.16%; the culture proven endophthalmitis was 0.02% and 0.08%. Gram-positive cocci (44%-64.8%; commonly, Staphylococcus species), and Gram-negative bacilli (26.2%-43%; commonly Pseudomonas species) were common bacteria in south India. Fungi (16.7%-70%; commonly Aspergillus flavus) were the common organisms in north India. Pseudomonas aeruginosa (73.3%) was the major organism in cluster infections.

conclusionsThe incidence of postcataract surgery clinical endophthalmitis in India is nearly similar to the world literature. There is a regional difference in microbiological spectrum. A registry with regular and uniform national reporting will help formulate region specific management guidelines.

Indexed as

Cataract ExtractionEndophthalmitisEye InfectionsForecastingHumansIncidenceIndiaMicrobial Sensitivity TestsSurgical Wound Infection

Identifiers

PMID28820151
PMCPMC5598176

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.