Evidence map›Paper›PMID 28820128›Full record

ArticleEmerging infectious diseases2017

Molecular Antimicrobial Resistance Surveillance for Neisseria gonorrhoeae, Northern Territory, Australia.

David M Whiley, Ella Trembizki, Cameron Buckley, Kevin Freeman, Robert W Baird, Miles Beaman, Marcus Chen, Basil Donovan, Ratan L Kundu, Christopher K Fairley and 10 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Surveillance systems to monitor antimicrobial resistance inEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Pooled it
  2. The Prevalence of Antimicrobial ResistantInternational journal of environmental research and public health · 2022
    Pooled it
  3. Article
  4. Molecular surveillance to monitor the prevalence of tetracycline resistance inmedRxiv : the preprint server for health sciences · 2024
    Article
  5. Review
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  9. Levels ofJournal of clinical microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

David M Whiley
Ella Trembizki
Cameron Buckley
Kevin Freeman
Robert W Baird
Miles Beaman
Marcus Chen
Basil Donovan
Ratan L Kundu
Christopher K Fairley
Rebecca Guy
Tiffany Hogan
John M Kaldor
Mahdad Karimi
Athena Limnios
David G Regan
Nathan Ryder
Jiunn-Yih Su
James Ward
Monica M Lahra

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neisseria gonorrhoeae antimicrobial resistance (AMR) is a globally recognized health threat; new strategies are needed to enhance AMR surveillance. The Northern Territory of Australia is unique in that 2 different first-line therapies, based primarily on geographic location, are used for gonorrhea treatment. We tested 1,629 N. gonorrhoeae nucleic acid amplification test-positive clinical samples, collected from regions where ceftriaxone plus azithromycin or amoxicillin plus azithromycin are recommended first-line treatments, by using 8 N. gonorrhoeae AMR PCR assays. We compared results with those from routine culture-based surveillance data. PCR data confirmed an absence of ceftriaxone resistance and a low level of azithromycin resistance (0.2%), and that penicillin resistance was <5% in amoxicillin plus azithromycin regions. Rates of ciprofloxacin resistance and penicillinase-producing N. gonorrhoeae were lower when molecular methods were used. Molecular methods to detect N. gonorrhoeae AMR can increase the evidence base for treatment guidelines, particularly in settings where culture-based surveillance is limited.

Indexed as

Public Health SurveillanceAdultAmoxicillinAnti-Bacterial AgentsAzithromycinCeftriaxoneCiprofloxacinDrug Resistance, BacterialFemaleGonorrheaHumansMaleMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingAmoxicillinAnti-Bacterial AgentsAzithromycinCeftriaxoneCiprofloxacinPenicillinsAMRantimicrobial drugsantimicrobial resistanceAustraliabacteriaculturegonococcusgonorrheamolecularNeisseria gonorrhoeaeNorthern Territorysurveillance

Identifiers

PMID28820128
PMCPMC5572890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.