ArticleEJNMMI research2017
Introducing navigation during melanoma-related sentinel lymph node procedures in the head-and-neck region.
Article in EJNMMI research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Evaluation of Preoperative and Intraoperative Mobile Gamma Camera Imaging in Sentinel Lymph Node Biopsy for Melanoma Independent of Preoperative Lymphoscintigraphy.The Journal of surgical research · 2023Trial
- Utilization of extended-reality technologies in the field of medical radiation.Radiological physics and technology · 2026Review
- Indocyanine Green (ICG) Fluorescence vs. Tc-99m Lymphoscintigraphy: Optimizing Sentinel Lymph Node Detection in Cutaneous Melanoma-A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Artificial intelligence-assisted spatial correction of augmented reality projections; implementing radiation mapping during radioguided robotic surgery.npj digital surgery · 2026Article
- The Journey of Sentinel Lymph Node Biopsy in Cutaneous Melanoma: A Brief Narrative Review from Scalpel to Smart Tech.Medicina (Kaunas, Lithuania) · 2025Review
- Article
- The current status and future prospects for molecular imaging-guided precision surgery.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022Review
- Evaluation of camera-based freehand SPECT in preoperative sentinel lymph node mapping for melanoma patients.EJNMMI research · 2020Article
- Repurposing Molecular Imaging and Sensing for Cancer Image-Guided Surgery.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020Review
- Sentinel Node Identification in Melanoma: Current Clinical Impact, New Emerging SPECT Radiotracers and Technological Advancements. An Update of the Last Decade.Current radiopharmaceuticals · 2020Review
- Detection of Sentinel Lymph Nodes with Near-Infrared Imaging in Malignancies.Molecular imaging and biology · 2019Review
- Emerging Intraoperative Imaging Modalities to Improve Surgical Precision.Molecular imaging and biology · 2018Review
- Feasibility of fluorescence lymph node imaging in colon cancer: FLICC.Techniques in coloproctology · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntraoperative sentinel node (SN) identification in patients with head-and-neck malignancies can be challenging due to unexpected drainage patterns and anatomical complexity. Here, intraoperative navigation-based guidance technologies may provide outcome. In this study, gamma camera-based freehandSPECT was evaluated in combination with the hybrid tracer ICG- MATERIALS AND
methodsEight patients with melanoma located in the head-and-neck area were included. Indocyanine green (ICG)-
resultsPreoperatively, 15 SNs were identified, of which 14 were identified using freehandSPECT. Navigation towards these nodes using the freehandSPECT approach was successful in 13 nodes. Fluorescence imaging provided optical confirmation of the navigation accuracy in all patients. In addition, fluorescence imaging allowed for the identification of (clustered) SNs that could not be identified based on navigation alone.
conclusionsThe use of gamma camera-based freehandSPECT aids intraoperative lesion identification and, with that, supports the transition from pre- to intraoperative imaging via augmented reality display and directional guidance.
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