Trial reportEuropean radiology2018
Radiation dose with digital breast tomosynthesis compared to digital mammography: per-view analysis.
Trial report in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Italian guidelines for the use of digital breast tomosynthesis in breast cancer screening programmes: GRADE-ADOLOPMENT of the European guidelines.La Radiologia medica · 2026Guideline
- Diagnostic performance of tomosynthesis plus synthetic mammography versus full-field digital mammography with or without tomosynthesis in breast cancer screening: A systematic review and meta-analysis.International journal of cancer · 2025Pooled it
- Performance of Digital Breast Tomosynthesis, Synthetic Mammography, and Digital Mammography in Breast Cancer Screening: A Systematic Review and Meta-Analysis.Journal of the National Cancer Institute · 2021Pooled it
- Radiation exposure and screening yield by digital breast tomosynthesis compared to mammography: results of the TOSYMA Trial breast density related.European radiology · 2025Trial
- A randomized controlled trial of digital breast tomosynthesis versus digital mammography in population-based screening in Bergen: interim analysis of performance indicators from the To-Be trial.European radiology · 2019Trial
- Design and measurement of 3D-printed variable-morphology and variable-density breast phantoms for mammography and breast CT dose assessment.3D printing in medicine · 2026Article
- Screening mammography: Any room for reading improvement without AI?European radiology · 2026Article
- AAPM/EFOMP TG282 versus dance dosimetry for digital breast tomosynthesis in the assessment pathway of a breast screening program.Medical physics · 2026Article
- Low dose photon-counting digital breast tomosynthesis: comparison with a commercially available tomosynthesis unit in the detection and characterization of breast carcinomas.La Radiologia medica · 2026Article
- Predicting the quality of digital mammography from the perspective of detectability of microcalcifications: A Radiomics approach.Medical physics · 2025Article
- Deep Learning in Digital Breast Tomosynthesis: Current Status, Challenges, and Future Trends.MedComm · 2025Review
- An update on multimodal imaging strategies for nipple discharge: from detection to decision.Insights into imaging · 2025Article
- Contrast-enhanced mammography improves patient access to functional breast imaging.Journal of medical imaging and radiation oncology · 2025Review
- Using automated software evaluation to improve the performance of breast radiographers in tomosynthesis screening.European radiology · 2024Article
- Breast Cancer Screening Using Inverse Modeling of Surface Temperatures and Steady-State Thermal Imaging.Cancers · 2024Article
- Screening the Implant-Augmented Breast with Digital Breast Tomosynthesis: Is Tomosynthesis Necessary for Non-implant-Displaced Views?Journal of breast imaging · 2024Article
- Phantom-based analysis of variations in automatic exposure control across three mammography systems: implications for radiation dose and image quality in mammography, DBT, and CEM.European radiology experimental · 2024Article
- Radiation doses received in the UK breast screening programmes 2019-2023.The British journal of radiology · 2024Article
- Radioactive seed localization is a safe and effective tool for breast cancer surgery: an evaluation of over 25,000 cases.Journal of radiological protection : official journal of the Society for Radiological Protection · 2024Article
- Establishing national diagnostic reference levels in radiography, mammography, and dual-energy x-ray absorptiometry services in Ireland and comparing these with European diagnostic reference levels.European radiology · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare radiation dose delivered by digital mammography (FFDM) and breast tomosynthesis (DBT) for a single view.
methods4,780 FFDM and 4,798 DBT images from 1,208 women enrolled in a screening trial were used to ground dose comparison. Raw images were processed by an automatic software to determine volumetric breast density (VBD) and were used together with exposure data to compute the mean glandular dose (MGD) according to Dance's model. DBT and FFDM were compared in terms of operation of the automatic exposure control (AEC) and MGD level.
resultsStatistically significant differences were found between FFDM and DBT MGDs for all views (CC: MGD
conclusionsOur findings show a modest increase of radiation dose to the breast by tomosynthesis compared to FFDM. Given the emerging role of DBT, its use in conjunction with synthetic 2D images should not be deterred by concerns regarding radiation burden, and should draw on evidence of potential clinical benefit. KEY POINTS: • Most studies compared tomosynthesis in combination with mammography vs. mammography alone. • There is some concern about the dose increase with tomosynthesis. • Clinical data show a small increase in radiation dose with tomosynthesis. • Synthetic 2D images from tomosynthesis at zero dose reduce potential harm. • The small dose increase should not be a barrier to use of tomosynthesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.