Evidence map›Paper›PMID 28819766›Full record

ReviewStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2018

[German S3 guideline for renal cell carcinoma : Presentation and discussion of essential aspects for the radiation oncologist].

Arndt-Christian Müller, Birgitt van Oorschot, Oliver Micke, Matthias Guckenberger

Abstract readReview
PubMed Publisher
In one paragraph

Review in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Treating the Chameleon: Radiotherapy in the management of Renal Cell Cancer.Clinical and translational radiation oncology · 2019
    Review
  4. Combination of stereotactic radiotherapy and targeted therapy: patterns-of-care survey in German-speaking countries.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Arndt-Christian MüllerDepartment of Radiation Oncology, Eberhard Karls University, Hoppe-Seyler-Str. 3, 72076, Tübingen, Deutschland. arndt-christian.mueller@med.uni-tuebingen.de.
Birgitt van OorschotDepartment of Radiation Oncology, Julius Maximilians University, Josef-Schneider-Str. 11, 97080, Würzburg, Deutschland.
Oliver MickeDepartment of Radiotherapy and Radiation Oncology, Franziskus Hospital Bielefeld, Kiskerstraße 26, 33615, Bielefeld, Deutschland.
Matthias GuckenbergerDepartment of Radiation Oncology, University of Zurich, Rämistrasse 100, 8001, Zürich, Schweiz.
Francis Hospital · DEUniversity of Tübingen · DEUniversity of Würzburg · DEUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aim to introduce and discuss the statements and recommendations of the German S3 guideline on renal cell cancer for daily practice of radiation oncologists.

methodsThis report comprises indication, treatment decision, dose prescription and current literature including treatment of oligometastatic disease.

resultsAccording to different stages of the disease and the structure of the guideline we focus on five treatment situations and recommendations for decision making: (1) Neo-/adjuvant treatment before or after nephrectomy: No indication for radiotherapy. (2) Small renal mass: Stereotactic ablative radiotherapy is currently seen as experimental option due to small patient numbers reported in the literature. However, local tumor control achieved by SBRT appears favourable with >90% at 2 years. (3) Oligometastasis: Radiation treatment with higher local doses or stereotactic treatment is possible after interdisciplinary discussion. Indications for palliative (4) and symptomatic treatment (5) are not different compared to other tumor entities.

conclusionCurrently, there is no evidence-based indication for radiation treatment in the primary setting (adjuvant/neoadjuvant or definitive) of renal cell cancer. In the future stereotactic radiotherapy should have a stronger role in the treatment of medically inoperable patients with primary renal cell cancer and especially in the setting of oligometastasis.

Indexed as

Guideline AdherenceRadiosurgeryRadiotherapy, AdjuvantCarcinoma, Renal CellCombined Modality TherapyGermanyHumansInterdisciplinary CommunicationIntersectoral CollaborationKidney NeoplasmsNeoadjuvant TherapyNeoplasm MetastasisNeoplasm StagingPalliative CareGuidelineOligometastasisRenal cell cancerSBRTStereotactic radiotherapy

Identifiers

PMID28819766
OpenAlexW2765549372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.