SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2018
Neuromuscular electrical stimulation is effective in strengthening the quadriceps muscle after anterior cruciate ligament surgery.
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Neuromuscular electrical stimulation improves stability and function in chronic ankle instability: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- The effectiveness of neuromuscular electrical stimulation on pain, function, and quadriceps muscle strength in adults with patellofemoral pain: A systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Pooled it
- Pooled it
- Effect of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in medicine · 2021Pooled it
- Effects of electrical stimulation combined with strength training on pain, muscle strength and lower-limb biomechanics in patellofemoral pain patients: a randomized controlled trial.BMC musculoskeletal disorders · 2025Trial
- Effect of neuromuscular electrical stimulation combined with early rehabilitation therapy on mechanically ventilated patients: a prospective randomized controlled study.BMC pulmonary medicine · 2023Trial
- A Novel Mobile App-based Neuromuscular Electrical Stimulation Therapy for the Management of Knee Osteoarthritis: Results From an Extension Study of a Randomized, Double-blind, Sham-controlled, Multicenter Trial.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022Trial
- Quadriceps muscle strength recovery with the use of high tone power therapy after anterior cruciate ligament reconstruction: a randomized controlled trial.BMC musculoskeletal disorders · 2021Trial
- Utility of Neuromuscular Electrical Stimulation to Preserve Quadriceps Muscle Fiber Size and Contractility After Anterior Cruciate Ligament Injuries and Reconstruction: A Randomized, Sham-Controlled, Blinded Trial.The American journal of sports medicine · 2020Trial
- Hop tests can result in higher limb symmetry index values than isokinetic strength and leg press tests in patients following ACL reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Trial
- Acute responses of inflammatory markers, glucose, and myoglobin in blood following neuromuscular electrical stimulation.European journal of applied physiology · 2026Article
- Evolution of pre- and post-operative balance characteristics in patients undergoing anterior cruciate ligament reconstruction: implications for rehabilitation.Frontiers in bioengineering and biotechnology · 2026Article
- Anterior cruciate ligament reconstruction in the modern era: A patient-centered approach.World journal of clinical cases · 2025Article
- Neuromuscular Electrical Stimulation Enhances Lower Limb Muscle Synergies During Jumping in Martial Artists Post-Anterior Cruciate Ligament Reconstruction: A Randomized Crossover Trial.Bioengineering (Basel, Switzerland) · 2025Article
- The Impact of Neuromuscular Stimulation on the Rehabilitation Outcomes of Patients Following Joint Replacement Surgery: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2025Review
- Motorpoint Heatmap of the Hamstring Muscles to Facilitate Neuromuscular Electrical Stimulation.Annals of biomedical engineering · 2025Article
- Regional Patellar Tendon Strain in the Short- and Long-term After ACL Reconstruction Using Bone-Patellar Tendon-Bone Autograft.The American journal of sports medicine · 2025Article
- Effects of Neuromuscular Electrical Stimulation on Quadriceps Femoris Muscle Strength and Knee Joint Function in Patients After ACL Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Orthopaedic journal of sports medicine · 2025Review
- Four-year comparative analysis of return to sport and psychological recovery following ACL revision: Artificial ligament vs. anterior tibial tendon allograft.Journal of orthopaedic translation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeReduced ability to contract the quadriceps muscles is often found immediately following anterior cruciate ligament (ACL) surgery. This can lead to muscle atrophy and decreased function. Application of neuromuscular electrical stimulation (NMES) may be a useful adjunct intervention to ameliorate these deficits following ACL surgery. The purpose of this review was to determine whether NMES in addition to standard physical therapy is superior to standard physical therapy alone in improving quadriceps strength or physical function following ACL surgery.
methodsA computer-assisted literature search was conducted utilizing PubMed, CINAHL, PEDro and Cochrane Library databases for randomized clinical trials where patients after ACL surgery received NMES with the outcome of muscle strength and/or physical function. Random effect models were used to pool summary estimates using standardized mean differences (SMD) for strength outcomes. Physical function outcomes were assessed qualitatively. Methodological quality was assessed from the Physiotherapy Evidence Database (PEDro)-score.
resultsEleven studies met our inclusion criteria; results from six of these were pooled in the meta-analysis showing a statistically significant short-term effect of NMES (4-12 weeks) after surgery compared to standard physical therapy [SMD = 0.73 (95% CI 0.29, 1.16)]. Physical function also improved significantly more in the NMES groups. PEDro scores ranged from 3/10 to 7/10 points.
conclusionNMES in addition to standard physical therapy appears to significantly improve quadriceps strength and physical function in the early post-operative period compared to standard physical therapy alone. LEVEL OF EVIDENCE: I.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.