Evidence map›Paper›PMID 28819601›Full record

ArticleJournal of orthopaedic case reports

Carcinoma of Unknown Primary Mimicking Multiple Myeloma.

Vanamali B Seetharamaiah, B Sunil, M K Padmanabha, N Sparsha

Abstract readCase Reports
In one paragraph

Article in Journal of orthopaedic case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vanamali B SeetharamaiahDepartment of Orthopedics, Bangalore Medical College and Research Institute, Victoria Hospital, KR Road, Bengaluru, Karnataka, India.
B SunilDepartment of Orthopedics, Bangalore Medical College and Research Institute, Victoria Hospital, KR Road, Bengaluru, Karnataka, India.
M K PadmanabhaDepartment of Orthopedics, Bangalore Medical College and Research Institute, Victoria Hospital, KR Road, Bengaluru, Karnataka, India.
N SparshaDepartment of Orthopedics, Bangalore Medical College and Research Institute, Victoria Hospital, KR Road, Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPathological fractures due to secondaries in the bone are common with carcinoma of lung, breast, prostate, and in multiple myeloma. Multiple pathological fractures after a trivial fall, indicating metastases warrants detailed investigations for the search of primary. Skeletal secondaries should be strongly suspected in addition to obvious diagnosis of multiple myeloma in such cases. CASE REPORT: We report a case of pathological fractures at multiple sites: The vertebral column, proximal shaft of femur, and contralateral fracture neck of femur. This patient presented with typical features of multiple myeloma, but on complete evaluation was found to be due to extensive metastases in the bones secondary to adenocarcinoma, the primary site of which remained unknown, despite extensive search and evaluation, making it a case of carcinoma of unknown primary.

conclusionWhile dealing with patients with extensive skeletal lesions and pathological fractures, secondaries due to adenocarcinoma elsewhere should be kept in mind along with other probabilities such as multiple myeloma.

Indexed as

carcinoma of unknown primarymultiple myelomaPathological fractures

Identifiers

PMID28819601
PMCPMC5553835

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.