Evidence map›Paper›PMID 28819339›Full record

SynthesisBehavioural neurology2017

Depression after Stroke in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.

Akin Ojagbemi, Onoja Akpa, Fisayo Elugbadebo, Mayowa Owolabi, Bruce Ovbiagele

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Behavioural neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.International journal of methods in psychiatric research · 2026
    Pooled it
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  6. Efficacy of Fluoxetine for Post-Ischemic Stroke Depression in Tanzania.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Trial
  7. Article
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  15. From stroke to depression: The need for systematic screening for post-stroke depression.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
    Article
  16. Article
  17. Article
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  20. Depression in Sub-Saharan Africa.IBRO neuroscience reports · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akin OjagbemiCollege of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID 0000-0001-7612-8017
Onoja AkpaCollege of Medicine, University of Ibadan, Ibadan, Nigeria.
Fisayo ElugbadeboUniversity College Hospital, Ibadan, Nigeria.
Mayowa OwolabiCollege of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID 0000-0003-1146-3070
Bruce OvbiageleKwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Funding

Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
NHGRI NIH HHS U54 HG007479
6 · The paper itself

Abstract

objectiveWe aimed to conduct a systematic review and meta-analysis of prevalence and characteristics of poststroke depression (PSD) in sub-Saharan Africa (SSA).

methodsWe searched Medline, PsycINFO, and African Journals OnLine using keywords for stroke and depression and the .mp. operator for all 54 SSA countries/regions. Further information was retrieved through a manual search of references from relevant published and unpublished articles. We included only peer-reviewed original studies with epidemiological or experimental designs, conducted random-effect meta-analysis, and identified the most commonly associated factors by weight (inverse of variance method).

resultsSeventeen studies, comprising 1483 stroke survivors, met the criteria for syntheses. The pooled frequency of clinically diagnosed PSD was 31% (95% CI = 26%-36%), versus 13.9% in healthy control pairs. Prevalence did not vary much across healthcare settings but was affected by methods of depression ascertainment. PSD was significantly associated with low education, cognitive impairment, physical disability, poor quality of life, and divorced marital status.

conclusionAlmost 1 in 3 individuals with stroke in SSA has clinical depression. Despite limitations around quality of identified studies, results of the present systematic review overlap with findings in the global literature and highlight useful targets for the design and trial of tailored intervention for PSD in SSA.

Indexed as

Africa South of the SaharaDepressionDepressive DisorderHumansMarital StatusPrevalenceQuality of LifeStroke

Identifiers

PMID28819339
PMCPMC5551463

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.