Evidence map›Paper›PMID 28819283›Full record

ArticleLeukemia2017

The C-terminal multimerization domain is essential for leukemia development by CBFβ-SMMHC in a mouse knockin model.

L Zhao, H Alkadi, E M Kwon, T Zhen, J Lichtenberg, L Alemu, J Cheng, A D Friedman, P P Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L ZhaoOncogenesis and Development Section, NHGRI, NIH, Bethesda, MD, USA.
H AlkadiOncogenesis and Development Section, NHGRI, NIH, Bethesda, MD, USA.
E M KwonOncogenesis and Development Section, NHGRI, NIH, Bethesda, MD, USA.
T ZhenOncogenesis and Development Section, NHGRI, NIH, Bethesda, MD, USA.
J LichtenbergOncogenesis and Development Section, NHGRI, NIH, Bethesda, MD, USA.
L AlemuOncogenesis and Development Section, NHGRI, NIH, Bethesda, MD, USA.
J ChengTransgenic Mouse Core, NHGRI, NIH, Bethesda, MD, USA.
A D FriedmanDivision of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
P P LiuOncogenesis and Development Section, NHGRI, NIH, Bethesda, MD, USA.

Funding

NHGRI/DIR Embryonic Stem Cell and Transgenic Mouse CoreZICHG200349 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BURGESS, SHAWN M · 2010 to 2025
$23.8M
MOLECULAR PATHOGENESIS OF CHROMOSOME 16 INVERSION INHUMAN LEUKEMIAZIAHG000030 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI LIU, PAUL · 2009 to 2025
$15.8M
MOLECULAR PATHOGENESIS OF CHROMOSOME 16 INVERSION INHUMAN LEUKEMIAZ01HG000030 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI LIU, PU PAUL · 1995 to 2008
$2.5M
Intramural NIH HHS Z01 HG000030
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCarcinogenesisCore Binding Factor alpha SubunitsEpigenetic RepressionHeterozygoteLeukemiaMiceMice, TransgenicMutationMyosin Heavy ChainsOncogene Proteins, FusionProtein DomainsTranscription, GeneticCBFbeta-MYH11 fusion proteinCore Binding Factor alpha SubunitsMyosin Heavy ChainsOncogene Proteins, Fusion

Identifiers

PMID28819283
PMCPMC5718931

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.