Evidence map›Paper›PMID 28819257›Full record

ArticleScientific reports2017

Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner.

Danushka K Wijesundara, Wenbo Yu, Ben J C Quah, Preethi Eldi, John D Hayball, Kerrilyn R Diener, Ilia Voskoboinik, Eric J Gowans, Branka Grubor-Bauk

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Danushka K WijesundaraVirology Laboratory, The Basil Hetzel Institute for Translational Health Research, The University of Adelaide, Adelaide, South Australia, Australia. danushka.wijesundara@adelaide.edu.au.
Wenbo YuTranslational Oncology Laboratory, Centre for Cancer Biology, Adelaide, South Australia, Australia.
Ben J C QuahCancer & Vascular Biology Laboratory, The John Curtin School of Medical Research, Canberra, The Australian Capital Territory, Australia.
Preethi EldiExperimental Therapeutics Laboratory, Sansom Institute for Health Research, Adelaide, South Australia, Australia.
John D HayballExperimental Therapeutics Laboratory, Sansom Institute for Health Research, Adelaide, South Australia, Australia.
Kerrilyn R DienerExperimental Therapeutics Laboratory, Sansom Institute for Health Research, Adelaide, South Australia, Australia.ORCID 0000-0001-8417-5542
Ilia VoskoboinikKiller Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Eric J GowansVirology Laboratory, The Basil Hetzel Institute for Translational Health Research, The University of Adelaide, Adelaide, South Australia, Australia.
Branka Grubor-BaukVirology Laboratory, The Basil Hetzel Institute for Translational Health Research, The University of Adelaide, Adelaide, South Australia, Australia.
Basil Hetzel Institute · AUUniversity of South Australia · AUACT GovernmentCentre for Cancer Biology · AUPeter MacCallum Cancer Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of cost-effective vaccines capable of inducing robust CD8

Indexed as

Antigen PresentationAnimalsAntigensCell ProliferationDendritic CellsHEK293 CellsHumansMice, Inbred C57BLPerforinTime FactorsT-Lymphocytes, CytotoxicVaccines, DNAAntigensPerforinVaccines, DNA

Identifiers

PMID28819257
PMCPMC5561019
OpenAlexW2744924239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.