ArticleNature communications2017
Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed, 144 citations in OpenAlex.
- Article
- Deorphanization of the odorant receptor CsepOR1 identifies a biphasic behavioral modulator in Coccinella septempunctata (Coleoptera: Coccinellidae).Pest management science · 2026Article
- Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Genome and transcriptome-based identification and expression profiling of chemosensory gene families across developmental stages and tissues in Sirex noctilio (Hymenoptera: Siricidae).Insect molecular biology · 2026Article
- Early hexapod genomes reveal the deep origin of insect gustatory and odorant receptors.Nature communications · 2026Article
- Adaptive evolution of odorant receptors is associated with elaborations of social organization in ants.Molecular biology and evolution · 2026Article
- Consistent Cuticular Hydrocarbon Discrimination of Alkane Mixtures with Proportional Differences in the Ant Camponotus floridanus.Journal of chemical ecology · 2026Article
- Independent Evolution of Linear and Branched Cuticular Hydrocarbons in Ants: A Hypothesis.Insects · 2026Article
- Molecular bases of insect odorant receptor function: specificity and evolution.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Sensitivity to cuticular hydrocarbons across the odorant receptor family in the Indian jumping ant,Frontiers in insect science · 2026Article
- Distribution and efficacy of ingested dsRNA targeting tissue-specific genes in the Argentine ant, Linepithema humile.PloS one · 2026Article
- Identification of two odorant receptors tuned to alarm pheromone compounds in the honey bee Apis mellifera.Communications biology · 2025Article
- Article
- The alkenes Z9-CNature communications · 2025Article
- Chemosensation drives divergent social behavior in Drosophila.Communications biology · 2025Article
- Transcriptional interference gates monogenic odorant receptor expression in ants.Current biology : CB · 2025Article
- Caste- and environment-associated differential expression of olfactory receptors in pest ants.Scientific reports · 2025Article
- Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants.bioRxiv : the preprint server for biology · 2025Article
- Article
- Ancestral complexity and constrained diversification of the ant olfactory system.Proceedings. Biological sciences · 2025Article
12 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors at 6 institutions in 1 country.
Funding
Abstract
Eusocial insects use cuticular hydrocarbons as components of pheromones that mediate social behaviours, such as caste and nestmate recognition, and regulation of reproduction. In ants such as Harpegnathos saltator, the queen produces a pheromone which suppresses the development of workers' ovaries and if she is removed, workers can transition to a reproductive state known as gamergate. Here we functionally characterize a subfamily of odorant receptors (Ors) with a nine-exon gene structure that have undergone a massive expansion in ants and other eusocial insects. We deorphanize 22 representative members and find they can detect cuticular hydrocarbons from different ant castes, with one (HsOr263) that responds strongly to gamergate extract and a candidate queen pheromone component. After systematic testing with a diverse panel of hydrocarbons, we find that most Harpegnathos saltator Ors are narrowly tuned, suggesting that several receptors must contribute to detection and discrimination of different cuticular hydrocarbons important in mediating eusocial behaviour.Cuticular hydrocarbons (CHC) mediate the interactions between individuals in eusocial insects, but the sensory receptors for CHCs are unclear. Here the authors show that in ants such as H. saltator, the 9-exon subfamily of odorant receptors (HsOrs) responds to CHCs, and ectopic expression of HsOrs in Drosophila neurons imparts responsiveness to CHCs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.