Evidence map›Paper›PMID 28818991›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Immune Modulation Therapy and Imaging: Workshop Report.

Anthony F Shields, Paula M Jacobs, Mario Sznol, Michael M Graham, Ron N Germain, Lawrence G Lum, Elizabeth M Jaffee, Elisabeth G E de Vries, Sridhar Nimmagadda, Annick D Van den Abbeele and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Phenomic Imaging.Phenomics (Cham, Switzerland) · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. European journal of nuclear medicine and molecular imaging · 2020
    Article
  10. Review
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 3 countries.

Anthony F ShieldsKarmanos Cancer Institute, Wayne State University, Detroit, Michigan shieldsa@karmanos.org.
Paula M JacobsNational Cancer Institute, Bethesda, Maryland.
Mario SznolYale University, New Haven, Connecticut.
Michael M GrahamUniversity of Iowa, Iowa City, Iowa.
Ron N GermainNational Cancer Institute, Bethesda, Maryland.
Lawrence G LumUniversity of Virginia, Charlottesville, Virginia.
Elizabeth M JaffeeJohns Hopkins University, Baltimore, Maryland.
Elisabeth G E de VriesUniversity of Groningen Medical Center, Groningen, The Netherlands.
Sridhar NimmagaddaJohns Hopkins University, Baltimore, Maryland.
Annick D Van den AbbeeleDana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
David K LeungBristol-Myers Squibb, Princeton, New Jersey; and.
Anna M WuCrump Institute for Molecular Imaging, David Geffen School of Medicine at UCLA, Los Angeles, California.
Elad SharonNational Cancer Institute, Bethesda, Maryland.
Lalitha K ShankarNational Cancer Institute, Bethesda, Maryland.
National Cancer Institute · USJohns Hopkins University · USBrigham and Women's Hospital · USBristol-Myers Squibb (Sweden) · SEInstitute for Molecular Medicine · USThe Barbara Ann Karmanos Cancer Institute · USUniversity of Groningen · NLUniversity of Iowa · USUniversity of Virginia · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Multiscale Analysis of Immune ResponsesZIAAI000545 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GERMAIN, RONALD N · 2009 to 2025
$29.4M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

A workshop at the National Cancer Institute on May 2, 2016, considered the current state of imaging in assessment of immunotherapy. Immunotherapy has shown some remarkable and prolonged responses in the treatment of tumors. However, responses are variable and frequently delayed, complicating the evaluation of new immunotherapy agents and customizing treatment for individual patients. Early anatomic imaging may show that a tumor has increased in size, but this could represent pseudoprogression. On the basis of imaging, clinicians must decide if they should stop, pause, or continue treatment. Other imaging technologies and approaches are being developed to improve the measurement of response in patients receiving immunotherapy. Imaging methods that are being evaluated include radiomic methods using CT, MRI, and

Indexed as

Diagnostic ImagingImmunotherapyResearch ReportHumansNeoplasmsbiomarkersimaging cancerimmunotherapy

Identifiers

PMID28818991
PMCPMC5868498
OpenAlexW2745670095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.