ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018
Pseudoreference Regions for Glial Imaging with
Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Trial
- Towards a Whole-Body Assessment of Pain Using the 18 kDa Translocator Protein (TSPO) as a Broad-Spectrum Imaging Marker of Inflammation.European journal of pain (London, England) · 2026Review
- Evidence for brain glial activity in chronic migraine patients: a [European journal of nuclear medicine and molecular imaging · 2025Article
- Brain inflammation and its predictive value for post-operative pain in total knee arthroplasty patients.Brain, behavior, and immunity · 2025Article
- Microglia's Phenotypic Heterogeneity in Pain Pathogenesis and Electroacupuncture Analgesia: Mechanisms and Therapeutic Potential.Journal of pain research · 2025Review
- Review
- Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [Brain, behavior, and immunity · 2024Article
- In vivo translocator protein in females with autism spectrum disorder: a pilot study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Neuroimmune activation and increased brain aging in chronic pain patients after the COVID-19 pandemic onset.Brain, behavior, and immunity · 2024Article
- A blood-free modeling approach for the quantification of the blood-to-brain tracer exchange in TSPO PET imaging.Frontiers in neuroscience · 2024Article
- Time course of neuroinflammation after human stroke - a pilot study using co-registered PET and MRI.BMC neurology · 2023Article
- Positron Emission Tomography of Neuroimmune Responses in Humans: Insights and Intricacies.Seminars in nuclear medicine · 2023Review
- Molecular neuroimaging of inflammation in HIV.Clinical and experimental immunology · 2022Review
- Article
- Neuroimmune signatures in chronic low back pain subtypes.Brain : a journal of neurology · 2022Article
- Multimodal Investigation of Neuroinflammation in Aviremic Patients With HIV on Antiretroviral Therapy and HIV Elite Controllers.Neurology(R) neuroimmunology & neuroinflammation · 2022Article
- Imaging immunological processes from blood to brain in amyotrophic lateral sclerosis.Clinical and experimental immunology · 2021Review
- Supervised clustering for TSPO PET imaging.European journal of nuclear medicine and molecular imaging · 2021Review
- [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- A pilot [Brain, behavior, & immunity - health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
The translocator protein (TSPO) is a commonly used imaging target to investigate neuroinflammation. Although TSPO imaging demonstrates great promise, its signal exhibits substantial interindividual variability, which needs to be accounted for to uncover group effects that are truly reflective of neuroimmune activation. Recent evidence suggests that relative metrics computed using pseudoreference approaches can minimize within-group variability and increase sensitivity to detect physiologically meaningful group differences. Here, we evaluated various ratio approaches for TSPO imaging and compared them with standard kinetic modeling techniques, analyzing 2 different disease cohorts. Patients with chronic low back pain (cLBP) or amyotrophic lateral sclerosis (ALS) and matching healthy controls received
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.