ArticleNeuroImage2017
Direct detection of neural activity in vitro using magnetic resonance electrical impedance tomography (MREIT).
Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Clinical Applications of Electrical Conductivity Imaging Using MRI.Journal of magnetic resonance imaging : JMRI · 2026Review
- Magnetic Detection of Neural Activity by Nanocoil Transducers.Nano letters · 2024Article
- Emerging trends and hot spots on electrical impedance tomography extrapulmonary applications.Heliyon · 2022Article
- Analytic modeling of neural tissue: II. Nonlinear membrane dynamics.AIP advances · 2022Article
- Enhanced magnetic transduction of neuronal activity by nanofabricated inductors quantified via finite element analysis.Journal of neural engineering · 2022Article
- Electromagnetic Properties and the Basis for CDI, MREIT, and EPT.Advances in experimental medicine and biology · 2022Article
- Development and testing of implanted carbon electrodes for electromagnetic field mapping during neuromodulation.Magnetic resonance in medicine · 2020Article
- Evaluation of magnetohydrodynamic effects in magnetic resonance electrical impedance tomography at ultra-high magnetic fields.Magnetic resonance in medicine · 2019Article
- Functional magnetic resonance electrical impedance tomography (fMREIT) sensitivity analysis using an active bidomain finite-element model of neural tissue.Magnetic resonance in medicine · 2019Article
- Analytic modeling of conductively anisotropic neural tissue.Journal of applied physics · 2018Article
- The effect of potassium chloride onBiomedical physics & engineering express · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
We describe a sequence of experiments performed in vitro to verify the existence of a new magnetic resonance imaging contrast - Magnetic Resonance Electrical Impedance Tomography (MREIT) -sensitive to changes in active membrane conductivity. We compared standard deviations in MREIT phase data from spontaneously active Aplysia abdominal ganglia in an artificial seawater background solution (ASW) with those found after treatment with an excitotoxic solution (KCl). We found significant increases in MREIT treatment cases, compared to control ganglia subject to extra ASW. This distinction was not found in phase images from the same ganglia using no imaging current. Further, significance and effect size depended on the amplitude of MREIT imaging current used. We conclude that our observations were linked to changes in cell conductivity caused by activity. Functional MREIT may have promise as a more direct method of functional neuroimaging than existing methods that image correlates of blood flow such as BOLD fMRI.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.