Evidence map›Paper›PMID 28818042›Full record

ArticleBMC bioinformatics2017

Coreference annotation and resolution in the Colorado Richly Annotated Full Text (CRAFT) corpus of biomedical journal articles.

K Bretonnel Cohen, Arrick Lanfranchi, Miji Joo-Young Choi, Michael Bada, William A Baumgartner, Natalya Panteleyeva, Karin Verspoor, Martha Palmer, Lawrence E Hunter

Abstract read
In one paragraph

Article in BMC bioinformatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Large language models for bioinformatics.Quantitative biology (Beijing, China) · 2026
    Review
  2. Transformers and large language models in healthcare: A review.Artificial intelligence in medicine · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

K Bretonnel CohenComputational Bioscience Program, University of Colorado School of Medicine, Denver, CO, USA. kevin.cohen@gmail.com.
Arrick LanfranchiDepartment of Linguistics, University of Colorado at Boulder, Boulder, Colorado, USA.
Miji Joo-Young ChoiSchool of Computing and Information Systems, The University of Melbourne, Melbourne, Australia.
Michael BadaComputational Bioscience Program, University of Colorado School of Medicine, Denver, CO, USA.
William A BaumgartnerComputational Bioscience Program, University of Colorado School of Medicine, Denver, CO, USA.
Natalya PanteleyevaComputational Bioscience Program, University of Colorado School of Medicine, Denver, CO, USA.
Karin VerspoorSchool of Computing and Information Systems, The University of Melbourne, Melbourne, Australia.
Martha PalmerComputational Bioscience Program, University of Colorado School of Medicine, Denver, CO, USA.
Lawrence E HunterComputational Bioscience Program, University of Colorado School of Medicine, Denver, CO, USA.

Funding

Technology Development for a MolBio Knowledge-BaseR01LM008111 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2004 to 2021
$9.7M
Bio Text NLPR01LM009254 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2006 to 2018
$5.9M
Construction of a Full Text Corpus for Biomedical Text MiningG08LM009639 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2007 to 2009
$471k
NLM NIH HHS G08 LM009639NLM NIH HHS R01 LM008111NLM NIH HHS R01 LM009254
6 · The paper itself

Abstract

backgroundCoreference resolution is the task of finding strings in text that have the same referent as other strings. Failures of coreference resolution are a common cause of false negatives in information extraction from the scientific literature. In order to better understand the nature of the phenomenon of coreference in biomedical publications and to increase performance on the task, we annotated the Colorado Richly Annotated Full Text (CRAFT) corpus with coreference relations.

resultsThe corpus was manually annotated with coreference relations, including identity and appositives for all coreferring base noun phrases. The OntoNotes annotation guidelines, with minor adaptations, were used. Interannotator agreement ranges from 0.480 (entity-based CEAF) to 0.858 (Class-B3), depending on the metric that is used to assess it. The resulting corpus adds nearly 30,000 annotations to the previous release of the CRAFT corpus. Differences from related projects include a much broader definition of markables, connection to extensive annotation of several domain-relevant semantic classes, and connection to complete syntactic annotation. Tool performance was benchmarked on the data. A publicly available out-of-the-box, general-domain coreference resolution system achieved an F-measure of 0.14 (B3), while a simple domain-adapted rule-based system achieved an F-measure of 0.42. An ensemble of the two reached F of 0.46. Following the IDENTITY chains in the data would add 106,263 additional named entities in the full 97-paper corpus, for an increase of 76% percent in the semantic classes of the eight ontologies that have been annotated in earlier versions of the CRAFT corpus.

conclusionsThe project produced a large data set for further investigation of coreference and coreference resolution in the scientific literature. The work raised issues in the phenomenon of reference in this domain and genre, and the paper proposes that many mentions that would be considered generic in the general domain are not generic in the biomedical domain due to their referents to specific classes in domain-specific ontologies. The comparison of the performance of a publicly available and well-understood coreference resolution system with a domain-adapted system produced results that are consistent with the notion that the requirements for successful coreference resolution in this genre are quite different from those of the general domain, and also suggest that the baseline performance difference is quite large.

Indexed as

Periodicals as TopicData MiningSemanticsAnaphoraAnnotationBenchmarkingCoreferenceCorpusResolution

Identifiers

PMID28818042
PMCPMC5561560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.