Evidence map›Paper›PMID 28817785›Full record

ReviewBiochemistry and cell biology = Biochimie et biologie cellulaire2018

Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder.

Yohaan Fernandes, Desire M Buckley, Johann K Eberhart

Abstract readReview
In one paragraph

Review in Biochemistry and cell biology = Biochimie et biologie cellulaire, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Zebrafish models of fetal alcohol spectrum disorders.Genesis (New York, N.Y. : 2000) · 2021
    Review
  10. Review
  11. Animal models of gene-alcohol interactions.Birth defects research · 2020
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yohaan FernandesMolecular Biosciences, University of Texas at Austin, Austin, TX 78713, USA.
Desire M BuckleyMolecular Biosciences, University of Texas at Austin, Austin, TX 78713, USA.
Johann K EberhartMolecular Biosciences, University of Texas at Austin, Austin, TX 78713, USA.

Funding

Cross-Cultural Assessment of FASDU24AA014811 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY · 2003 to 2026
$13.1M
Genetic Screens in Zebrafish to Identify Gene-Ethanol InteractionsR01AA023426 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI JOHANN K EBERHART · 2015 to 2026
$3.0M
NIAAA NIH HHS R01 AA023426NIAAA NIH HHS U24 AA014811
6 · The paper itself

Abstract

The term fetal alcohol spectrum disorder (FASD) refers to the entire suite of deleterious outcomes resulting from embryonic exposure to alcohol. Along with other reviews in this special issue, we provide insight into how animal models, specifically the zebrafish, have informed our understanding of FASD. We first provide a brief introduction to FASD. We discuss the zebrafish as a model organism and its strengths for alcohol research. We detail how zebrafish has been used to model some of the major defects present in FASD. These include behavioral defects, such as social behavior as well as learning and memory, and structural defects, disrupting organs such as the brain, sensory organs, heart, and craniofacial skeleton. We provide insights into how zebrafish research has aided in our understanding of the mechanisms of ethanol teratogenesis. We end by providing some relatively recent advances that zebrafish has provided in characterizing gene-ethanol interactions that may underlie FASD.

Indexed as

Disease Models, AnimalFetal Alcohol Spectrum DisordersZebrafishAnimalsEthanolHumansTeratogenesisEthanolbrain and behaviorcerveau et comportementenvironmentenvironnementfetal alcohol spectrum disordergeneticsgénétiquepoisson-zèbretrouble du spectre de l’alcoolisation fœtalezebrafish

Identifiers

PMID28817785
PMCPMC7413215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.