ArticleMedicine and science in sports and exercise2018
High-Intensity Exercise Enhances Conduit Artery Vascular Function in Older Adults.
Article in Medicine and science in sports and exercise, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Skipping breakfast does not accelerate the hyperglycemia-induced endothelial dysfunction but reduces blood flow of the brachial artery in young men.European journal of applied physiology · 2024Trial
- The acute effects of exercise intensity and inorganic nitrate supplementation on vascular health in females after menopause.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Trial
- Effects of continuous hypoxia on flow-mediated dilation in the cerebral and systemic circulation: on the regulatory significance of shear rate phenotype.The journal of physiological sciences : JPS · 2022Trial
- Acute High Intensity Interval Exercise Promotes Circulating Progenitor Cell Mobilization and Improves Microcirculation in Patients with Chronic Heart Failure.Journal of cardiovascular development and disease · 2026Article
- Optimizing the predictive validity of NIRS kinetic profiles to predict aerobic capacity from a resting skeletal muscle occlusion test.Experimental physiology · 2026Article
- Do modest changes in skin temperature affect the measurement of micro- and macrovascular function?Frontiers in physiology · 2026Article
- Impact of acute and chronic cycling exercise on microvascular reactivity of the upper and lower extremity muscles in young healthy females.Journal of exercise science and fitness · 2025Article
- Vascular function after acute aerobic exercise in adults with and without type 2 diabetes mellitus.Scientific reports · 2025Article
- Proton-Sensing G Protein-Coupled Receptors and Their Potential Role in Exercise Regulation of Arterial Function.Biomolecules · 2025Review
- Understanding Endothelial Dysfunction and Its Role in Ischemic Stroke After the Outbreak of Recanalization Therapies.International journal of molecular sciences · 2024Review
- Is It Possible to Train the Endothelium?-A Narrative Literature Review.Life (Basel, Switzerland) · 2024Review
- The impact of leg position on muscle blood flow and oxygenation during low-intensity rhythmic plantarflexion exercise.European journal of applied physiology · 2023Article
- Differences in Blood Flow Patterns and Endothelial Shear Stress at the Carotid Artery Using Different Exercise Modalities and Intensities.Frontiers in physiology · 2022Article
- Effect of exercise on vascular function in hypertension patients: A meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2022Review
- High-intensity exercise in hypoxia improves endothelial function via increased nitric oxide bioavailability in C57BL/6 mice.Acta physiologica (Oxford, England) · 2021Article
- Acute hypotension attenuates brachial flow-mediated dilation in young healthy men.European journal of applied physiology · 2020Article
- Prior cycling exercise does not prevent endothelial dysfunction after resistance exercise.European journal of applied physiology · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeModulation of vascular function follows an exercise intensity-dependent pattern in young adults. This study aimed to investigate the potential intensity-dependent effects of an acute bout of exercise on conduit and resistance artery function in healthy older adults.
methodsEleven healthy older adults (five males/six females, 66 ± 1 yr) completed 30 min of recumbent cycling at 50%-55% (low intensity) and 75%-80% (high intensity) of their age-predicted HRmax on two separate study visits. Doppler ultrasound measures of brachial artery flow-mediated dilation (FMD) and reactive hyperemia were taken at baseline, 10 min postexercise, and 1 h postexercise. In addition, cardiovascular hemodynamics and brachial shear rate were measured every 5 min during exercise.
resultsBrachial artery FMD was enhanced 10 min after high-intensity exercise (4.8% ± 0.2% to 9.1% ± 0.3%, P < 0.01), but not low-intensity (4.7% ± 0.2% to 6.2% ± 0.3%, P = 0.54) exercise. Peak and total (area under the curve) blood flow during reactive hyperemia (measures of resistance artery function) were enhanced 10 min postexercise for both intensities (peak low intensity, 372 ± 31 to 444 ± 37 mL·min; peak high intensity, 391 ± 30 to 455 ± 28 mL·min; total low intensity, 142 ± 16 to 205 ± 20 mL; total high intensity, 158 ± 14 to 240 ± 25 mL; main effect of time for both, P < 0.05). However, the magnitude of change in peak and the total blood flow were not different between exercise intensities (interaction effect; P = 0.56 and P = 0.97, respectively). Independent of exercise intensity, FMD returned to baseline 1 h after exercise (high, 5.9% ± 0.3%; low, 5.1% ± 0.1%; both P > 0.05).
conclusionOur data indicate that high-intensity exercise acutely enhances conduit artery function in healthy older adults. In addition, an acute bout of exercise enhances resistance artery function independent of intensity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.