ReviewNutrients2017
Human Milk and Allergic Diseases: An Unsolved Puzzle.
Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed.
- Exploring Immune Development in Infants With Moderate to Severe Atopic Dermatitis.Frontiers in immunology · 2018Trial
- Efficacy of probiotic-supplemented formula in treating chronic diarrhea in children aged 6-43 months: evidence based on a randomized controlled trial.Gut pathogens · 2026Article
- Human milk oligosaccharide secretion dynamics during breastfeeding and its antimicrobial role: A systematic review.World journal of clinical pediatrics · 2025Article
- Macronutrients, Micronutrients, and Malnutrition: Effects of Nutrition on Immune Function in Infants and Young Children.Nutrients · 2025Review
- Dietary 3'-sialyllactose reduces sensitization and type 2 inflammation in a house dust mite induced acute allergic asthma model.Frontiers in allergy · 2025Article
- Article
- Human Milk Microbiome-A Review of Scientific Reports.Nutrients · 2024Review
- Dietary Factors May Delay Tolerance Acquisition in Food Protein-Induced Allergic Proctocolitis.Nutrients · 2023Observational
- Winds of change a tale of: asthma and microbiome.Frontiers in microbiology · 2023Review
- Association between breastfeeding and prevalence of allergies among children in the Academy Teaching Charity Hospital, Sudan.Qatar medical journal · 2023Article
- Allergen Content and Protease Activity in Milk Feeds from Mothers of Preterm Infants.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2022Observational
- Maternal Diet Is Associated with Human Milk Oligosaccharide Profile.Molecular nutrition & food research · 2022Article
- Using Community Ecology Theory and Computational Microbiome Methods To Study Human Milk as a Biological System.mSystems · 2022Review
- Analysing the protection from respiratory tract infections and allergic diseases early in life by human milk components: the PRIMA birth cohort.BMC infectious diseases · 2022Observational
- S3 guideline Allergy Prevention.Allergologie select · 2022Article
- Perinatal exposure to foodborne inorganic nanoparticles: A role in the susceptibility to food allergy?Frontiers in allergy · 2022Review
- The human milk proteome and allergy of mother and child: Exploring associations with protein abundances and protein network connectivity.Frontiers in immunology · 2022Article
- Feeding in the first six months of life is associated with the probability of having bronchiolitis: a cohort study in Spain.International breastfeeding journal · 2021Article
- Infant Feeding Practices During the First Postnatal Year and Risk of Asthma and Allergic Disease During the First 6 Years of Life.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2021Article
- Provider recommendations and maternal practices when providing breast milk to children with immunoglobulin E-mediated food allergy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is conflicting evidence on the protective role of breastfeeding in relation to the development of allergic sensitisation and allergic disease. Studies vary in methodology and definition of outcomes, which lead to considerable heterogeneity. Human milk composition varies both within and between individuals, which may partially explain conflicting data. It is known that human milk composition is very complex and contains variable levels of immune active molecules, oligosaccharides, metabolites, vitamins and other nutrients and microbial content. Existing evidence suggests that modulation of human breast milk composition has potential for preventing allergic diseases in early life. In this review, we discuss associations between breastfeeding/human milk composition and allergy development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.