Evidence map›Paper›PMID 28816594›Full record

ReviewJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2018

Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease.

Manus J Donahue, Eric Achten, Petrice M Cogswell, Frank-Erik De Leeuw, Colin P Derdeyn, Rick M Dijkhuizen, Audrey P Fan, Rashid Ghaznawi, Jeremy J Heit, M Arfan Ikram and 18 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Macro- and microvascular contributions to cerebral structural alterations in patients with asymptomatic carotid artery stenosis.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  12. VICTR: Venous transit time imaging by changes in TMagnetic resonance in medicine · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Manus J Donahue1 Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Eric Achten5 Department of Radiology and Nuclear Medicine, Universiteit Gent, Gent, Belgium.
Petrice M Cogswell1 Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Frank-Erik De Leeuw6 Radboud University, Nijmegen Medical Center, Donders Institute Brain Cognition & Behaviour, Center for Neuroscience, Department of Neurology, Nijmegen, The Netherlands.
Colin P Derdeyn7 Department of Radiology and Neurology, University of Iowa, Iowa City, IA, USA.
Rick M Dijkhuizen8 Biomedical MR Imaging and Spectroscopy Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
Audrey P Fan9 Department of Radiology, Stanford University, Stanford, CA, USA.
Rashid Ghaznawi10 Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Jeremy J Heit11 Department of Radiology, Neuroimaging and Neurointervention Division, Stanford University, CA, USA.ORCID 0000-0003-1055-8000
M Arfan Ikram12 Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
Peter Jezzard14 Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.ORCID 0000-0001-7912-2251
Lori C Jordan15 Department of Pediatrics, Division of Pediatric Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Eric Jouvent16 Department of Neurology, AP-HP, Lariboisière Hospital, Paris, France.
Linda Knutsson17 Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Richard Leigh19 National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
David S Liebeskind20 Neurovascular Imaging Research Core, UCLA, Los Angeles, CA, USA.
Weili Lin21 Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Thomas W Okell14 Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Adnan I Qureshi22 Department of Neurology, Zeenat Qureshi Stroke Institute, St. Cloud, MN, USA.
Charlotte J Stagg23 Oxford Centre for Human Brain Activity, University of Oxford, Oxford, UK.
Matthias Jp van Osch24 Department of Radiology, Leiden Medical Center, Leiden, The Netherlands.ORCID 0000-0001-7034-8959
Peter Cm van Zijl17 Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jennifer M Watchmaker1 Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Max Wintermark11 Department of Radiology, Neuroimaging and Neurointervention Division, Stanford University, CA, USA.
Ona Wu26 Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA.
Greg Zaharchuk11 Department of Radiology, Neuroimaging and Neurointervention Division, Stanford University, CA, USA.
Jinyuan Zhou17 Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jeroen Hendrikse10 Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Using MRI to Understand Disease States that Occur at the Interface of the Brain and the Cerebral CirculationZIANS003151 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI LEIGH, RICHARD · 2015 to 2023
$6.8M
Quantification of Glymphatic Dysfunction in Patients with Alzheimer's Disease and Related DementiasR01NR015079 · NINR · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DONAHUE, MANUS J · 2014 to 2022
$3.9M
Cerebrovascular Reserve Imaging with Simultaneous PET/MRI Using Arterial Spin Labeling and Deep LearningR01EB025220 · NIBIB · STANFORD UNIVERSITY · PI ZAHARCHUK, GREGORY GEORGE · 2018 to 2021
$2.8M
Imaging collaterals and tissue metabolism in patients with Moyamoya syndromeR01NS097763 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DONAHUE, MANUS J · 2016 to 2020
$1.7M
Characterizing Hemodynamic Compensation and Stroke Risk in Stenosis PatientsR01NS078828 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DONAHUE, MANUS J · 2012 to 2016
$1.6M
Institutional Predoctoral Training Program in Biomedical Imaging ScienceT32EB014841 · NIBIB · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2013 to 2017
$771k
NIBIB NIH HHS R01 EB025220NIBIB NIH HHS T32 EB014841NICHD NIH HHS U54 HD083211NIGMS NIH HHS T32 GM007347NINDS NIH HHS R01 NS078828NINDS NIH HHS R01 NS097763NINR NIH HHS R01 NR015079
6 · The paper itself

Abstract

Cerebrovascular disease (CVD) remains a leading cause of death and the leading cause of adult disability in most developed countries. This work summarizes state-of-the-art, and possible future, diagnostic and evaluation approaches in multiple stages of CVD, including (i) visualization of sub-clinical disease processes, (ii) acute stroke theranostics, and (iii) characterization of post-stroke recovery mechanisms. Underlying pathophysiology as it relates to large vessel steno-occlusive disease and the impact of this macrovascular disease on tissue-level viability, hemodynamics (cerebral blood flow, cerebral blood volume, and mean transit time), and metabolism (cerebral metabolic rate of oxygen consumption and pH) are also discussed in the context of emerging neuroimaging protocols with sensitivity to these factors. The overall purpose is to highlight advancements in stroke care and diagnostics and to provide a general overview of emerging research topics that have potential for reducing morbidity in multiple areas of CVD.

Indexed as

Cerebrovascular DisordersHumanscerebrovascular diseasehemodynamicsimagingmetabolismStroke

Identifiers

PMID28816594
PMCPMC6125970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.