Evidence map›Paper›PMID 28816581›Full record

ReviewNucleus (Austin, Tex.)2017

Novel functions for chromatin dynamics in mRNA biogenesis beyond transcription.

Catherine Dargemont, Anna Babour

Abstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Catherine Dargemonta Université Paris Diderot, Sorbonne Paris Cité, INSERM UMR944, CNRS UMR7212 , Hôpital St. Louis 1, Paris , France.ORCID 0000-0002-7075-9608
Anna Baboura Université Paris Diderot, Sorbonne Paris Cité, INSERM UMR944, CNRS UMR7212 , Hôpital St. Louis 1, Paris , France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first step of gene expression results in the production of mRNA ribonucleoparticles (mRNPs) that are exported to the cytoplasm via the NPC for translation into the cytoplasm. During this process, the mRNA molecule synthesized by RNA polymerase II (Pol II) undergoes extensive maturation, folding and packaging events that are intimately coupled to its synthesis. All these events take place in a chromatin context and it is therefore not surprising that a growing number of studies recently reported specific contributions of chromatin dynamics to various steps of mRNP biogenesis. In this extra view, we replace our recent findings highlighting the contribution of the yeast chromatin remodeling complex ISW1 to nuclear mRNA quality control in the context of the recent literature.

Indexed as

Transcription, GeneticAnimalsChromatinChromatin Assembly and DisassemblyHistonesHumansRNA, MessengerRNA SplicingChromatinHistonesRNA, Messengerchromatin dynamicsISW1mRNA biogenesismRNA quality control

Identifiers

PMID28816581
PMCPMC5703233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.