Evidence map›Paper›PMID 28816463›Full record

ArticleThe journal of physical chemistry. B2017

Signaling-Related Mobility Changes in Bacterial Chemotaxis Receptors Revealed by Solid-State NMR.

Maryam Kashefi, Lynmarie K Thompson

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A chemoreceptor conformational equilibrium controlled by signaling inputs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. The structural logic of dynamic signaling in the Escherichia coli serine chemoreceptor.Protein science : a publication of the Protein Society · 2024
    Article
  6. The Structural Logic of Dynamic Signaling in thebioRxiv : the preprint server for biology · 2024
    Article
  7. Structural signatures ofProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Article
  10. Studying bacterial chemosensory array with CryoEM.Biochemical Society transactions · 2021
    Review
  11. Article
  12. Advances in studying protein disorder with solid-state NMR.Solid state nuclear magnetic resonance · 2020
    Review
  13. Intrinsically disordered HAX-1 regulates CaBiochimica et biophysica acta. Biomembranes · 2020
    Article
  14. Article
  15. Carbon-nitrogen REDOR to identify ms-timescale mobility in proteins.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2019
    Article
  16. Conformational shifts in a chemoreceptor helical hairpin control kinase signaling inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  17. Article
  18. Review
  19. Review
  20. A zipped-helix cap potentiates HAMP domain control of chemoreceptor signaling.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maryam KashefiDepartment of Chemistry, ‡Program in Molecular and Cellular Biology, University of Massachusetts Amherst , Amherst, Massachusetts 01003, United States.
Lynmarie K ThompsonDepartment of Chemistry, ‡Program in Molecular and Cellular Biology, University of Massachusetts Amherst , Amherst, Massachusetts 01003, United States.ORCID 0000-0002-9447-6776
University of Massachusetts Amherst · US

Funding

Assembly and Function of Bacterial Chemotaxis Receptor Signaling ComplexesR01GM085288 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 2010 to 2013
$1.2M
NIGMS NIH HHS R01 GM085288
6 · The paper itself

Abstract

Bacteria employ remarkable membrane-bound nanoarrays to sense their environment and direct their swimming. Arrays consist of chemotaxis receptor trimers of dimers that are bridged at their membrane-distal tips by rings of two cytoplasmic proteins, a kinase CheA and a coupling protein CheW. It is not clear how ligand binding to the periplasmic domain of the receptor deactivates the CheA kinase bound to the cytoplasmic tip ∼300 Å away, but the mechanism is thought to involve changes in dynamics within the cytoplasmic domain. To test these proposals, we applied solid-state NMR mobility-filtered experiments to functional complexes of the receptor cytoplasmic fragment (U-

Indexed as

ChemotaxisNuclear Magnetic Resonance, BiomolecularSignal TransductionEscherichia coliEscherichia coli ProteinsMethyltransferasesCheR protein, E coliEscherichia coli ProteinsMethyltransferases

Identifiers

PMID28816463
PMCPMC5613836
OpenAlexW2748360277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.