ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018
Dopamine Synthesis Capacity is Associated with D2/3 Receptor Binding but Not Dopamine Release.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Pharmacological and non-pharmacological modulation of striatal dopamine release: a meta-analysis of [Molecular psychiatry · 2026Pooled it
- Methylphenidate undermines or enhances divergent creativity depending on baseline dopamine synthesis capacity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- Fronto-striatal dopamine D2 receptor availability is associated with cognitive variability in older individuals with low dopamine integrity.Scientific reports · 2021Trial
- Article
- Dopaminergic mechanisms supporting hippocampal postencoding dynamics in humans.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Resolving the heterogeneity of dopamine subsystems dysfunction in schizophrenia: a PET meta-analysis.Schizophrenia (Heidelberg, Germany) · 2025Review
- Striatal dopamine tone is positively associated with adiposity in humans as determined by PET using dual dopamine type-2 receptor antagonist tracers.Molecular psychiatry · 2025Article
- A dopaminergic basis of behavioral control.bioRxiv : the preprint server for biology · 2024Article
- Pathological and neurochemical correlates of locus coeruleus functional network activity.Biological psychology · 2024Article
- Striatal dopamine synthesis and cognitive flexibility differ between hormonal contraceptive users and nonusers.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Article
- Locus coeruleus catecholamines link neuroticism and vulnerability to tau pathology in aging.NeuroImage · 2022Article
- Striatal dopamine dissociates methylphenidate effects on value-based versus surprise-based reversal learning.Nature communications · 2022Article
- Elevated Dopamine Synthesis as a Mechanism of Cognitive Resilience in Aging.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Molecular Imaging of Central Dopamine in Obesity: A Qualitative Review across Substrates and Radiotracers.Brain sciences · 2022Review
- Associations among locus coeruleus catecholamines, tau pathology, and memory in aging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Effects of average reward rate on vigor as a function of individual variation in striatal dopamine.Psychopharmacology · 2022Article
- Functional dynamics of dopamine synthesis during monetary reward and punishment processing.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Dopamine and glutamate in individuals at high risk for psychosis: a meta-analysis of in vivo imaging findings and their variability compared to controls.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021Article
- Imaging synaptic dopamine availability in individuals at clinical high-risk for psychosis: a [Molecular psychiatry · 2021Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Positron Emission Tomography (PET) imaging allows the estimation of multiple aspects of dopamine function including dopamine synthesis capacity, dopamine release, and D2/3 receptor binding. Though dopaminergic dysregulation characterizes a number of neuropsychiatric disorders including schizophrenia and addiction, there has been relatively little investigation into the nature of relationships across dopamine markers within healthy individuals. Here we used PET imaging in 40 healthy adults to compare, within individuals, the estimates of dopamine synthesis capacity (K
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.