Evidence map›Paper›PMID 28816146›Full record

ArticleInternational journal of radiation oncology, biology, physics2017

Quality Assessment of Stereotactic Radiosurgery of a Melanoma Brain Metastases Model Using a Mouselike Phantom and the Small Animal Radiation Research Platform.

Cheng-Chia Wu, Kunal R Chaudhary, Yong Hum Na, David Welch, Paul J Black, Adam M Sonabend, Peter Canoll, Yvonne M Saenger, Tony J C Wang, Cheng-Shie Wuu and 2 more

Open access · greenAbstract read
In one paragraph

Article in International journal of radiation oncology, biology, physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Cheng-Chia WuDepartment of Radiation Oncology, Columbia University Medical Center, New York, New York.
Kunal R ChaudharyDepartment of Radiation Oncology, Columbia University Medical Center, New York, New York.
Yong Hum NaDepartment of Radiation Oncology, Columbia University Medical Center, New York, New York.
David WelchCenter for Radiological Research, Columbia University, New York, New York.
Paul J BlackDepartment of Radiation Oncology, Columbia University Medical Center, New York, New York.
Adam M SonabendDepartment of Neurological Surgery, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.
Peter CanollHerbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York; Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York.
Yvonne M SaengerHematology/Oncology, New York-Presbyterian/Columbia University Medical Center, New York, New York.
Tony J C WangDepartment of Radiation Oncology, Columbia University Medical Center, New York, New York; Department of Neurological Surgery, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.
Cheng-Shie WuuDepartment of Radiation Oncology, Columbia University Medical Center, New York, New York.
Tom K HeiCenter for Radiological Research, Columbia University, New York, New York; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York.
Simon K ChengDepartment of Radiation Oncology, Columbia University Medical Center, New York, New York. Electronic address: sc3225@cumc.columbia.edu.
Columbia University Irving Medical Center · USColumbia University · US

Funding

Sample Engineering CoreU19AI067773 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FORNACE, ALBERT J · 2005 to 2024
$105.4M
Targeting Kif11 to Treat Glioblastoma Invasion and ProliferationR01NS073610 · NINDS · MAYO CLINIC JACKSONVILLE · PI CANOLL, PETER, ELMQUIST, WILLIAM · 2012 to 2021
$4.3M
Small Animal CT Image Guided Xray Irradiation SystemS10OD010631 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WUU, CHENG-SHIE · 2012 to 2012
$590k
NIAID NIH HHS U19 AI067773NIH HHS S10 OD010631NINDS NIH HHS R01 NS073610
6 · The paper itself

Abstract

purposeTo establish a novel preclinical model for stereotactic radiosurgery (SRS) with combined mouselike phantom quality assurance in the setting of brain metastases. METHODS AND MATERIALS: C57B6 mice underwent intracranial injection of B16-F10 melanoma cells. T1-weighted postcontrast magnetic resonance imaging (MRI) was performed on day 11 after injection. The MRI images were fused with cone beam computed tomography (CBCT) images using the Small Animal Radiation Research Platform (SARRP). The gross tumor volume (GTV) was contoured using the MRI. A single sagittal arc using the 3 × 3 mm

resultsThe tumor volume on day 11, before intervention, was 2.48 ± 1.37 mm

conclusionsSingle-fraction SRS of 18 Gy delivered in a single arc can be delivered accurately with MRI T1-weighted postcontrast-based treatment planning. The mouse like phantom allows for verification of dose delivery and accuracy.

Indexed as

Phantoms, ImagingQuality Assurance, Health CareAnimalsBrain NeoplasmsCone-Beam Computed TomographyContrast MediaMagnetic Resonance ImagingMaleMelanomaMiceMice, Inbred C57BLMultimodal ImagingRadiosurgeryRadiotherapy DosageTime FactorsTumor BurdenContrast Media

Identifiers

PMID28816146
PMCPMC5675116
OpenAlexW2614385521

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.