Evidence map›Paper›PMID 28816006›Full record

ArticleJournal of cellular and molecular medicine2018

CD38 deficiency suppresses adipogenesis and lipogenesis in adipose tissues through activating Sirt1/PPARγ signaling pathway.

Ling-Fang Wang, Lian-Jie Miao, Xiao-Nv Wang, Cong-Cong Huang, Yi-Song Qian, Xuan Huang, Xiao-Lei Wang, Wan-Zhu Jin, Guang-Ju Ji, Mingui Fu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Genome-Wide Meta-Analysis of Blood Pressure Response to βJournal of the American Heart Association · 2019
    Pooled it
  2. Article
  3. Article
  4. Article
  5. CD38 in SLE CD4 T cells promotes CaNature communications · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. The Role of NADBiomedicines · 2023
    Review
  11. Review
  12. Review
  13. Mechanism of CD38 via NADInternational journal of medical sciences · 2023
    Review
  14. Article
  15. Harnessing NADCurrent heart failure reports · 2022
    Review
  16. Article
  17. NADMolecular and cellular biochemistry · 2022
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ling-Fang WangInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Lian-Jie MiaoInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Xiao-Nv WangInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Cong-Cong HuangInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Yi-Song QianInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Xuan HuangInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Xiao-Lei WangInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Wan-Zhu JinInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Guang-Ju JiNational Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Mingui FuDepartment of Basic Medical Science, Shock/Trauma Research Center, School of Medicine, University of Missouri Kansas City, Kansas City, MO, USA.
Ke-Yu DengInstitute of Translational Medicine, Nanchang University, Nanchang, China.
Hong-Bo XinInstitute of Translational Medicine, Nanchang University, Nanchang, China.ORCID 0000-0002-4257-207X
Nanchang University · CNChinese Academy of Sciences · CNUniversity of Missouri–Kansas City · US

Funding

Post-transcriptional Regulation of Cytokine ProductionR21AI103618 · NIAID · UNIVERSITY OF MISSOURI KANSAS CITY · PI FU, MINGUI · 2014 to 2015
$415k
NIAID NIH HHS R21 AI103618
6 · The paper itself

Abstract

It has been recently reported that CD38 was highly expressed in adipose tissues from obese people and CD38-deficient mice were resistant to high-fat diet (HFD)-induced obesity. However, the role of CD38 in the regulation of adipogenesis and lipogenesis is unknown. In this study, to explore the roles of CD38 in adipogenesis and lipogenesis in vivo and in vitro, obesity models were generated with male CD38

Indexed as

AdipogenesisLipogenesisSignal TransductionAdipocytesAdipose TissueADP-ribosyl Cyclase 1AnimalsCell DifferentiationEmbryo, MammalianFibroblastsMiceNADPPAR gammaSirtuin 1ADP-ribosyl Cyclase 1NADPPAR gammaSirtuin 1adipogenesisCD38lipogenesisperoxisome proliferator-activated receptor γSirt1

Identifiers

PMID28816006
PMCPMC5742727
OpenAlexW2749424906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.