Evidence map›Paper›PMID 28815436›Full record

SynthesisThe journal of headache and pain2017

Headache attributed to airplane travel: diagnosis, pathophysiology, and treatment - a systematic review.

Sebastian Bao Dinh Bui, Parisa Gazerani

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in The journal of headache and pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Rimegepant in airplane headache treatment: a case report.Journal of medical case reports · 2025
    Article
  2. Review
  3. Review
  4. Observational
  5. Review
  6. Headache and Barometric Pressure: a Narrative Review.Current pain and headache reports · 2019
    Review
  7. Diving Headache.Current pain and headache reports · 2019
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sebastian Bao Dinh BuiSMI®, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Parisa GazeraniSMI®, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark. gazerani@hst.aau.dk.
Aalborg University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeadache attributed to airplane travel, also named "airplane headache" (AH) is a headache that occurs during take-off and landing. Today, there are still uncertainties about the pathophysiology and treatment of AH. This systematic review was performed to facilitate identification of the existing literature on AH in order to discuss the current evidence and areas that remain to be investigated in AH.

methodsThe systematic literature search was performed in 3 relevant medical databases; PubMed, Scopus, and Embase. The search yielded 220 papers and the papers were sorted based on inclusion and exclusion criteria established for this study.

resultsThis systematic review included 39 papers. Main findings revealed that AH attacks are clinically stereotyped and appear mostly during landing phases. The headache presents as a severe painful headache that often disappears within 30 min. The pain is unilateral and localized in the fronto-orbital region. Sinus barotrauma has been considered as the main cause of AH. Nonsteroidal anti-inflammatory drugs and triptans have been taken by passengers with AH, to relieve the headache.

conclusionsBased on this systematic review, further studies seem required to investigate underlying mechanisms in AH and also to investigate the biological effects of nonsteroidal anti-inflammatory drugs and triptans for alleviating of AH. These studies would advance our understanding of AH pathogenesis and potential use of treatments that are not yet established.

Indexed as

AircraftTravelAnti-Inflammatory Agents, Non-SteroidalBarotraumaFrontal SinusHeadacheHumansTryptaminesAnti-Inflammatory Agents, Non-SteroidalTryptaminesAirplane headacheDiagnosisHeadache attributed to airplane travelNSAIDsPathophysiologySinus barotraumaTreatmentTriptans

Identifiers

PMID28815436
PMCPMC5559404
OpenAlexW2748627834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.