ArticleHernia : the journal of hernias and abdominal wall surgery2017
Characterization of host response, resorption, and strength properties, and performance in the presence of bacteria for fully absorbable biomaterials for soft tissue repair.
Article in Hernia : the journal of hernias and abdominal wall surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Coated poly-4-hydroxybutyrate (Phasix ST™) mesh is safe and effective for hiatal hernia repair: our institutional experience and review of the literature.Surgical endoscopy · 2024Pooled it
- Biosynthetic meshes in contaminated fields: where are we now? A systematic review and meta-analysis in humans.Hernia : the journal of hernias and abdominal wall surgery · 2023Pooled it
- Bio-resorbable poly-4-hydroxybutyrate (P4HB) mesh for abdominal wall reconstruction is effective in high-risk patients and contaminated abdomen.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Long-term outcome of prophylactic biosynthetic mesh reinforcement at the time of loop ileostomy reversal for colorectal cancer- results of a case-matched study.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Inguinal Hernia Repair Using Absorbable Biosynthetic Mesh Versus Permanent Polypropylene Mesh: A Preliminary Comparative Study of 1-Year Outcomes.Journal of abdominal wall surgery : JAWS · 2025Article
- Safety and tissue remodeling assay of small intestinal submucosa meshes using a modified porcine surgical hernia model.Scientific reports · 2024Article
- The Effects of Tissue Healing Factors in Wound Repair Involving Absorbable Meshes: A Narrative Review.Journal of clinical medicine · 2023Review
- Immune cell response to orthopedic and craniofacial biomaterials depends on biomaterial composition.Acta biomaterialia · 2023Article
- Fully resorbable poly-4-hydroxybutyrate (P4HB) mesh for soft tissue repair and reconstruction: A scoping review.Frontiers in surgery · 2023Article
- Outcomes of posterior component separation with transversus abdominis release (TAR) in large and other complex ventral hernias: a single-surgeon experience.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Successful conservative treatment of a poly-4-hydroxybutyrate mesh infection: A case report.Annals of medicine and surgery (2012) · 2021Article
- Regulatory science for hernia mesh: Current status and future perspectives.Bioactive materials · 2021Review
- Outcomes of Poly-4-hydroxybutyrate Mesh in Ventral Hernia Repair: A Systematic Review and Pooled Analysis.Plastic and reconstructive surgery. Global open · 2020Article
- Laparoscopic procedures impact on mast cell mediators, extracellular matrix and adhesion scoring system in rats.Annals of medicine and surgery (2012) · 2020Article
- Article
- When the Mesh Goes Away: An Analysis of Poly-4-Hydroxybutyrate Mesh for Complex Hernia Repair.Plastic and reconstructive surgery. Global open · 2019Article
- Contamination of hybrid hernia meshes compared to bioresorbable Phasix™ Mesh in a rabbit subcutaneous implant inoculation model.Annals of medicine and surgery (2012) · 2019Article
- Article
- A critical review of the in vitro and in vivo models for the evaluation of anti-infective meshes.Hernia : the journal of hernias and abdominal wall surgery · 2018Review
- Comment to: Characterization of host response, resorption, and strength properties, and performance in the presence of bacteria for fully absorbable biomaterials for soft tissue repair. Stoikes NFN, Scott J, Badhwar A, Deeken C, Voeller G.Hernia : the journal of hernias and abdominal wall surgery · 2018Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe objective was to evaluate the host response, resorption, and strength properties, and to assess the performance in the presence of bacteria for Phasix™ Mesh (Phasix™) and Gore
methodsIn a rat model, one mesh (2 × 2 cm) was implanted subcutaneously in n = 60 rats. Animals were euthanized after 2, 4, 8, 12, 16, or 24 weeks (n = 5/mesh/time point), and implant sites were assessed for host inflammatory response and overall fibrotic repair thickness. In a rabbit model, meshes (3.8 cm diameter) were bilaterally implanted in subcutaneous pockets in n = 20 rabbits (n = 10 rabbits/mesh) and inoculated with 10
resultsIn the rat study, Phasix™ and Bio-A
conclusionsHost response, resorption, repair thickness, strength, and bacterial colonization suggest a more stable and favorable outcome for monofilament, macroporous devices such as Phasix™ relative to multifilament, microporous devices such as Bio-A
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.