Evidence map›Paper›PMID 28815163›Full record

ReviewGlobal spine journal2017

Does Operative or Nonoperative Treatment Achieve Better Results in A3 and A4 Spinal Fractures Without Neurological Deficit?: Systematic Literature Review With Meta-Analysis.

Elke Rometsch, Maarten Spruit, Roger Härtl, Robert Alton McGuire, Brigitte Sandra Gallo-Kopf, Vasiliki Kalampoki, Frank Kandziora

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Global spine journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05003180 (SunBurst), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05003180 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

SunBurst (StUdy oN Burst Fractures) - a National, Multicenter, Register-based, Randomized Controlled Trial on Thoracolumbar Burst Fractures

TypeinterventionalSponsorUppsala UniversityRan2021 to 2036Enrolled202ConditionsThoracolumbar Burst FractureArmsSurgical stabilization
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. How reliable is the distinction between thoracolumbar AO type A3 and A4 fractures? A systematic literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Pooled it
  2. Percutaneous versus open pedicle screw fixation for treatment of type A thoracolumbar fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020
    Trial
  3. Inducing thoracolumbar burst fractures in human cadaveric specimens using a combined axial-flexion loading: a fracture simulation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Elke RometschAO Foundation, AO Clinical Investigation and Documentation (AOCID), Dübendorf, Switzerland.
Maarten SpruitSt Maartenskliniek Nijmegen, Ubbergen, Netherlands.
Roger HärtlNY Presbyterian Hospital-Weill Cornell Medical College, NY, USA.
Robert Alton McGuireUniversity of Mississippi Medical Center, Jackson, MS, USA.
Brigitte Sandra Gallo-KopfUniversity of Mississippi Medical Center, Jackson, MS, USA.
Vasiliki KalampokiAO Foundation, AO Clinical Investigation and Documentation (AOCID), Dübendorf, Switzerland.
Frank KandzioraBGU Klinik Frankfurt am Main, Frankfurt, Germany.
AO Foundation · CHUniversity of Mississippi Medical Center · USCornell University · USSint Maartenskliniek · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSystematic literature review with meta-analysis.

objectiveThoracolumbar (TL) fractures can be treated conservatively or surgically. Especially, the treatment strategy for incomplete and complete TL burst fractures (A3 and A4, AOSpine classification) in neurologically intact patients remains controversial. The aim of this work was to collate the clinical evidence on the respective treatment modalities.

methodsSearches were performed in PubMed and the Web of Science. Clinical and radiological outcome data were collected. For studies comparing operative with nonoperative treatment, the standardized mean differences (SMD) for disability and pain were calculated and methodological quality and risk of bias were assessed.

resultsFrom 1929 initial matches, 12 were eligible. Four of these compared surgical with conservative treatment. A comparative analysis of radiological results was not possible due to a lack of uniform reporting. Differences in clinical outcomes at follow-up were small, both between studies and between treatment groups. The SMD was 0.00 (95% CI -0.072, 0.72) for disability and -0.05 (95% CI -0.91, 0.81) for pain. Methodological quality was high in most studies and no evidence of publication bias was revealed.

conclusionsWe did not find differences in disability or pain outcomes between operative and nonoperative treatment of A3 and A4 TL fractures in neurologically intact patients. Notwithstanding, the available scores have been developed and validated for degenerative diseases; thus, their suitability in trauma may be questionable. Specific and uniform outcome parameters need to be defined and enforced for the evaluation of TL trauma.

Indexed as

A3 and A4 spinal fracturesAOSpine classificationconservative therapyfunctional outcomemeta-analysisneurologically intact patientssurgical therapythoracolumbar burst fractures

Identifiers

PMID28815163
PMCPMC5546683
OpenAlexW2742636547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.