Evidence map›Paper›PMID 28815145›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2017

Evolving Research Data Sharing Networks to Clinical App Sharing Networks.

Kavishwar B Wagholikar, Rahul Jain, Eliel Oliveira, Joshua Mandel, Jeffery Klann, Ricardo Colas, Prasad Patil, Kuladip Yadav, Kenneth D Mandl, Thomas Carton and 1 more

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. HL7 FHIR-based tools and initiatives to support clinical research: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. Extending i2b2 into a framework for semantic abstraction of EHR to facilitate rapid development and portability of Health IT applications.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kavishwar B WagholikarMassachussetts General Hospital, Boston, MA.
Rahul JainLouisiana Public Health Institute, LA.
Eliel OliveiraLouisiana Public Health Institute, LA.
Joshua MandelMassachussetts General Hospital, Boston, MA.
Jeffery KlannMassachussetts General Hospital, Boston, MA.
Ricardo ColasLouisiana Public Health Institute, LA.
Prasad PatilResearch Action for Health Network, LA.
Kuladip YadavPersistent Systems, India.
Kenneth D MandlMassachussetts General Hospital, Boston, MA.
Thomas CartonLouisiana Public Health Institute, LA.
Shawn N MurphyMassachussetts General Hospital, Boston, MA.

Funding

Instrumenting i2b2 for Improved Medication Research: Adding the Patient VoiceR01GM104303 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI MANDL, KENNETH D. · 2013 to 2016
$1.6M
A Framework to Enhance Decision Support by Invoking NLP: Methods and ApplicationsR00LM011575 · NLM · MASSACHUSETTS GENERAL HOSPITAL · PI WAGHOLIKAR, KAVISHWAR B. · 2016 to 2018
$749k
NIGMS NIH HHS R01 GM104303NLM NIH HHS R00 LM011575
6 · The paper itself

Abstract

Research networks for data sharing are growing into a large platform for pragmatic clinical trials to generate quality evidence for shared medical decision-making. Institutions partnering in the networks have made large investments in developing the infrastructure for sharing data. We investigate whether institutions partnering on Patient-Centered Outcomes Research Institute's (PCORI) network can share clinical apps. At two different sites, we imported patient data in PCORI's clinical data model (CDM) format into i2b2 repositories, and adapted the SMART-on-FHIR cell to perform CDM-to-FHIR translation, serving demographics, laboratory results and diagnoses. We performed manual validations and tested the platform using four apps from the SMART app gallery. Our study demonstrates an approach to extend the research infrastructure to allow the partnering institutions to run shared clinical apps, and highlights the involved challenges. Our results, tooling and publically accessible data service can potentially transform research networks into clinical app sharing networks and pave the way towards a learning health system.

Identifiers

PMID28815145
PMCPMC5543356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.