Evidence map›Paper›PMID 28814852›Full record

SynthesisInternational journal of chronic obstructive pulmonary disease2017

Prognostic variables and scores identifying the end of life in COPD: a systematic review.

Laura-Jane E Smith, Elizabeth Moore, Ifrah Ali, Liam Smeeth, Patrick Stone, Jennifer K Quint

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Summit Score Stratifies Mortality and Morbidity in Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2020
    Trial
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  12. Indian Society of Critical Care Medicine and Indian Association of Palliative Care Expert Consensus and Position Statements for End-of-life and Palliative Care in the Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura-Jane E SmithDepartment of Respiratory Epidemiology, Occupational Medicine and Public Health, Imperial College London.
Elizabeth MooreDepartment of Respiratory Epidemiology, Occupational Medicine and Public Health, Imperial College London.
Ifrah AliDepartment of Respiratory Epidemiology, Occupational Medicine and Public Health, Imperial College London.
Liam SmeethDepartment of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London.
Patrick StoneMarie Curie Palliative Care Research Unit, University College London, UK.
Jennifer K QuintDepartment of Respiratory Epidemiology, Occupational Medicine and Public Health, Imperial College London.

Funding

Marie Curie MCCC-FCH-18-UMarie Curie MCCC-FCO-11-UWellcome Trust
6 · The paper itself

Abstract

introductionCOPD is a major cause of mortality, and the unpredictable trajectory of the disease can bring challenges to end-of-life care. We aimed to investigate known prognostic variables and scores that predict prognosis in COPD in a systematic literature review, specifically including variables that contribute to risk assessment of patients for death within 12 months.

methodsWe conducted a systematic review on prognostic variables, multivariate score or models for COPD. Ovid MEDLINE, EMBASE, the Cochrane database, Cochrane CENTRAL, DARE and CINAHL were searched up to May 1, 2016.

resultsA total of 5,276 abstracts were screened, leading to 516 full-text reviews, and 10 met the inclusion criteria. No multivariable indices were developed with the specific aim of predicting all-cause mortality in stable COPD within 12 months. Only nine indices were identified from four studies, which had been validated for this time period. Tools developed using expert knowledge were also identified, including the Gold Standards Framework Prognostic Indicator Guidance, the RADboud Indicators of Palliative Care Needs, the Supportive and Palliative Care Indicators Tool and the Necesidades Paliativas program tool.

conclusionA number of variables contributing to the prediction of all-cause mortality in COPD were identified. However, there are very few studies that are designed to assess, or report, the prediction of mortality at or less than 12 months. The quality of evidence remains low, such that no single variable or multivariable score can currently be recommended.

Indexed as

Decision Support TechniquesAgedCause of DeathClinical Decision-MakingDisease ProgressionFemaleHumansLungMaleMiddle AgedMultivariate AnalysisOdds RatioPredictive Value of TestsPulmonary Disease, Chronic ObstructiveRisk AssessmentRisk FactorsCOPDend of lifepalliative care

Identifiers

PMID28814852
PMCPMC5546187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.