Evidence map›Paper›PMID 28814819›Full record

ArticleTetrahedron2017

Marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete clade MAR4.

Ratnakar N Asolkar, Ahilya Singh, Paul R Jensen, William Aalbersberg, Brad K Carté, Klaus-D Feussner, Ramesh Subramani, Antonio DiPasquale, Arnold L Rheingold, William Fenical

Abstract read
In one paragraph

Article in Tetrahedron, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Advances in the Study of Halogenated Natural Products.Current topics in medicinal chemistry · 2025
    Review
  5. Actinomycetes: A Source of Anticancer Metabolites.Current medicinal chemistry · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. MAR4Journal of natural products · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ratnakar N AsolkarCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, 92093-0204, USA.
Ahilya SinghInstitute of Applied Sciences, Faculty of Science, Technology and Environment, The University of the South Pacific, Laucala Campus, Private Mail Bag, Suva, Fiji.
Paul R JensenCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, 92093-0204, USA.
William AalbersbergInstitute of Applied Sciences, Faculty of Science, Technology and Environment, The University of the South Pacific, Laucala Campus, Private Mail Bag, Suva, Fiji.
Brad K CartéInstitute of Applied Sciences, Faculty of Science, Technology and Environment, The University of the South Pacific, Laucala Campus, Private Mail Bag, Suva, Fiji.
Klaus-D FeussnerInstitute of Applied Sciences, Faculty of Science, Technology and Environment, The University of the South Pacific, Laucala Campus, Private Mail Bag, Suva, Fiji.
Ramesh SubramaniDepartment of Biology, College of Engineering, Science & Technology (CEST), School of Science, Dept. of Biology, Fiji National University, Natabua Campus, Lautoka, Fiji.
Antonio DiPasqualeDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Arnold L RheingoldDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
William FenicalCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, 92093-0204, USA.

Funding

Exploration, conservation, & development of marine biodiversity in FijiU01TW007401 · FIC · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAY, MARK E · 2005 to 2013
$7.4M
The USP Center for Drug Discovery and ConservationU19TW007401 · FIC · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAY, MARK E · 2014 to 2018
$5.3M
FIC NIH HHS U01 TW007401FIC NIH HHS U19 TW007401
6 · The paper itself

Abstract

Six cytotoxic and antimicrobial metabolites of a new bromo-phenazinone class, the marinocyanins A-F (

Indexed as

BromophenazinonesMAR4 actinomyceteMeroterpenoids

Identifiers

PMID28814819
PMCPMC5555602

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.