ArticleScientific reports2017
On mechanism behind UV-A light enhanced antibacterial activity of gallic acid and propyl gallate against Escherichia coli O157:H7.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 82 citations in OpenAlex.
- Gallate-oriented surface engineering of lignin nanoparticles for enhanced antibacterial activity.Materials today. Bio · 2026Article
- A Targeted Mitigation Strategy for Freshwater Harmful Algal Blooms through the Release of a Small-Molecule Polyphenolic Algaecide from Clay Nanotubes.Environmental science & technology · 2026Article
- A Novel Approach for Reducing Enteropathogens Using LAB-Fermented Whey Solution and UV-C Light-Activated Gallic Acid.Foods (Basel, Switzerland) · 2026Article
- Preparation of Chitosan-Based Emodin Antimicrobial Functional Films and Application in the Preservation of Chilled Pork.Foods (Basel, Switzerland) · 2026Article
- Molecular Docking and Structure-Activity Relationship Study of Polyphenols with Antibacterial and Antibiotic-Modulating Properties.Microorganisms · 2026Article
- Comprehensive review on environmental pollution caused by 6PPD-quinone and remediation strategies.RSC advances · 2026Review
- Modulation of inflammatory and cuproptotic crosstalk by Ethyl and propyl gallate: a multi-targeted strategy against experimental colitis.Molecular biology reports · 2025Article
- Evaluation of antimicrobial potential of free gallic acid and its polyvinyl-based nano-formulation.Scientific reports · 2025Article
- Inactivation Efficacy of Combination Treatment of Propyl Gallate and UVA LED for Escherichia coli O157:H7 in Apple Juice.Journal of food science · 2025Article
- Gallic acid synergistically enhances the antibacterial activity of azithromycin in MRSA.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Synergistic antimicrobial activities of phenolic-rich extract derived from olive pomace and UV-A light against bacterial pathogens and their biofilms.Current research in food science · 2025Article
- Investigating the Antibacterial Effect of a Novel Gallic Acid-Based Green Sanitizer Formulation.Foods (Basel, Switzerland) · 2024Article
- The Potential Health Benefits of Gallic Acid: Therapeutic and Food Applications.Antioxidants (Basel, Switzerland) · 2024Review
- Antibacterial efficacy of copper-based metal-organic frameworks againstRSC advances · 2024Article
- An update on the potential mechanism of gallic acid as an antibacterial and anticancer agent.Food science & nutrition · 2023Review
- Immobilization of Natural Antimicrobial Compounds on Food-Grade Supports as a New Strategy to Preserve Fruit-Derived Foods.Foods (Basel, Switzerland) · 2023Review
- Friends against the Foe: Synergistic Photothermal and Photodynamic Therapy against Bacterial Infections.Pharmaceutics · 2023Review
- Quercetin mediated antimicrobial photodynamic treatment using blue light onCurrent research in food science · 2023Article
- In Silico Docking, Resistance Modulation and Biofilm Gene Expression in Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Gallic Acid-Functionalized, TiOMaterials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Possible mechanisms behind the enhanced antimicrobial activity of gallic acid (GA) and its ester propyl gallate (PG) in the presence of UV-A light against Escherichia coli O157:H7 were investigated. GA by itself is a mild antimicrobial and has a pro-oxidant ability. We found that the presence of UV-A light increases the uptake of GA by the bacteria. Once GA is internalized, the interaction between GA and UV-A induces intracellular ROS formation, leading to oxidative damage. Concurrently, GA + UV-A also inhibits the activity of superoxide dismutase (SOD), magnifying the imbalance of redox status of E. coli O157:H7. In addition to ROS induced damage, UV-A light and GA also cause injury to the cell membrane of E. coli O157:H7. UV-A exposed PG caused oxidative damage to the cell and significantly higher damage to the cell membrane than GA + UV-A treatment, explaining its higher effectiveness than GA + UV-A treatment. The findings presented here may be useful in developing new antimicrobial sanitation technologies for food and pharmaceutical industries.
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