ArticleNature communications2017
Pathogenic bacteria enhance dispersal through alteration of Drosophila social communication.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Artificial light source combined with functional microorganism improves reproductive performance of black soldier fly.Insect science · 2026Article
- Mother knows worst? Fungal infection enhances corn flavonoid of wogonin to inhibit Conogethes punctiferalis larval growth.Plant biotechnology journal · 2025Article
- Neuroecology of alcohol risk and reward: Methanol boosts pheromones and courtship success inScience advances · 2025Article
- Evolution of resistance and disease tolerance mechanisms to oral bacterial infection inOpen biology · 2025Article
- A plant virus manipulates both its host plant and the insect that facilitates its transmission.Science advances · 2025Article
- Effects of Microbes on Insect Host Physiology and Behavior Mediated by the Host Immune System.Insects · 2025Review
- Electroantennographic and Behavioral Responses of the Melon fly, Zeugodacus cucurbitae (Coquillett), to Volatile Compounds of Ridge Gourd, Luffa acutangular L.Journal of chemical ecology · 2024Article
- Genetic Variation in Trophic Avoidance Behaviour Shows Fruit Flies are Generally Attracted to Bacterial Substrates.Ecology and evolution · 2024Article
- The Sexual Dimorphism in Rectum and Protein Digestion Pathway Influence Sex Pheromone Synthesis in Male Bactrocera Dorsalis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Female semiochemicals stimulate male courtship but dampen female sexual receptivity.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Pathogen-Mediated Alterations of Insect Chemical Communication: From Pheromones to Behavior.Pathogens (Basel, Switzerland) · 2023Review
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- Pathogenic fungus uses volatiles to entice male flies into fatal matings with infected female cadavers.The ISME journal · 2022Article
- Analysis ofMicrobiology spectrum · 2022Article
- Host genetics and pathogen species modulate infection-induced changes in social aggregation behaviour.Biology letters · 2022Article
- Mutualism promotes insect fitness by fungal nutrient compensation and facilitates fungus propagation by mediating insect oviposition preference.The ISME journal · 2022Article
- Functional olfactory evolution iniScience · 2022Article
- Pre-copulatory reproductive behaviours are preserved inProceedings. Biological sciences · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Pathogens and parasites can manipulate their hosts to optimize their own fitness. For instance, bacterial pathogens have been shown to affect their host plants' volatile and non-volatile metabolites, which results in increased attraction of insect vectors to the plant, and, hence, to increased pathogen dispersal. Behavioral manipulation by parasites has also been shown for mice, snails and zebrafish as well as for insects. Here we show that infection by pathogenic bacteria alters the social communication system of Drosophila melanogaster. More specifically, infected flies and their frass emit dramatically increased amounts of fly odors, including the aggregation pheromones methyl laurate, methyl myristate, and methyl palmitate, attracting healthy flies, which in turn become infected and further enhance pathogen dispersal. Thus, olfactory cues for attraction and aggregation are vulnerable to pathogenic manipulation, and we show that the alteration of social pheromones can be beneficial to the microbe while detrimental to the insect host.Behavioral manipulation of host by pathogens has been observed in vertebrates, invertebrates, and plants. Here the authors show that in Drosophila, infection with pathogenic bacteria leads to increased pheromone release, which attracts healthy flies. This process benefits the pathogen since it enhances bacterial dispersal, but is detrimental to the host.
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Registered trials
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