ArticleJournal of neurophysiology2017
Muscle proprioceptors in adult rat: mechanosensory signaling and synapse distribution in spinal cord.
Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 61 citations in OpenAlex.
- Protocol for direct in vivo evaluation of the stretch reflex in adult mice.STAR protocols · 2026Article
- Ontogeny of the spinal cord dorsal horn.Science (New York, N.Y.) · 2026Article
- Review
- Computing muscle mechanical state variables from combined proprioceptive sensory feedback.Experimental physiology · 2025Article
- Using Electrical Muscle Stimulation to Enhance Electrophysiological Performance of Agonist-Antagonist Myoneural Interface.Bioengineering (Basel, Switzerland) · 2024Article
- Whole body vibration training promotes proprioceptive pathway for the treatment of stress urinary incontinence in rats.Translational andrology and urology · 2024Article
- Biophysical model of muscle spindle encoding.Experimental physiology · 2024Review
- Mechanosensory encoding in ex vivo muscle-nerve preparations.Experimental physiology · 2024Review
- Attenuation of muscle spindle firing with artificially increased series compliance during stretch of relaxed muscle.Experimental physiology · 2024Article
- The making of a proprioceptor: a tale of two identities.Trends in neurosciences · 2023Review
- Excitatory and Inhibitory Descending Commissural Interneurons Differentially Integrate Supraspinal and Segmental Sensory Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Structural Preservation Does Not Ensure Function at Sensory Ia-Motoneuron Synapses following Peripheral Nerve Injury and Repair.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Proprioception: A New Era Set in Motion by Emerging Genetic and Bionic Strategies?Annual review of physiology · 2023Review
- Article
- MS and GTO proprioceptor subtypes in the molecular genetic era: Opportunities for new advances and perspectives.Current opinion in neurobiology · 2022Review
- GABA facilitates spike propagation through branch points of sensory axons in the spinal cord.Nature neuroscience · 2022Article
- Neck Pain: Do We Know Enough About the Sensorimotor Control System?Frontiers in computational neuroscience · 2022Review
- Detection of epimuscular myofascial forces by Golgi tendon organs.Experimental brain research · 2022Article
- Motor Unit Discharge Patterns in Response to Focal Tendon Vibration of the Lower Limb in Cats and Humans.Frontiers in integrative neuroscience · 2022Article
- Mechanosensory encoding dysfunction emerges from cancer-chemotherapy interaction.Frontiers in molecular biosciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The characteristic signaling and intraspinal projections of muscle proprioceptors best described in the cat are often generalized across mammalian species. However, species-dependent adaptations within this system seem necessary to accommodate asymmetric scaling of length, velocity, and force information required by the physics of movement. In the present study we report mechanosensory responses and intraspinal destinations of three classes of muscle proprioceptors. Proprioceptors from triceps surae muscles in adult female Wistar rats anesthetized with isoflurane were physiologically classified as muscle spindle group Ia or II or as tendon organ group Ib afferents, studied for their firing responses to passive-muscle stretch, and in some cases labeled and imaged for axon projections and varicosities in spinal segments. Afferent projections and the laminar distributions of provisional synapses in rats closely resembled those found in the cat. Afferent signaling of muscle kinematics was also similar to reports in the cat, but rat Ib afferents fired robustly during passive-muscle stretch and Ia afferents displayed an exaggerated dynamic response, even after locomotor scaling was accounted for. These differences in mechanosensory signaling by muscle proprioceptors may represent adaptations for movement control in different animal species.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.