Evidence map›Paper›PMID 28814578›Full record

ArticleThe Biochemical journal2017

Genetic human prion disease modelled in PrP transgenic

Alana M Thackray, Alzbeta Cardova, Hanna Wolf, Lydia Pradl, Ina Vorberg, Walker S Jackson, Raymond Bujdoso

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Biochemical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Developmentally-regulated post-apocrine cell death ofFrontiers in cell and developmental biology · 2026
    Article
  2. Frontiers in neuroscience · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alana M ThackrayDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, U.K.
Alzbeta CardovaDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, U.K.
Hanna WolfGerman Center for Neurodegenerative Diseases (DZNE e.V.), Bonn, Germany.
Lydia PradlGerman Center for Neurodegenerative Diseases (DZNE e.V.), Bonn, Germany.
Ina VorbergGerman Center for Neurodegenerative Diseases (DZNE e.V.), Bonn, Germany.
Walker S JacksonGerman Center for Neurodegenerative Diseases (DZNE e.V.), Bonn, Germany.
Raymond BujdosoDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, U.K. rb202@cam.ac.uk.
German Center for Neurodegenerative Diseases · DEUniversity of Bonn · DE

Funding

Biotechnology and Biological Sciences Research Council BB/J014540/1Medical Research Council NC/K000462/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/K000462/1
6 · The paper itself

Abstract

Inherited human prion diseases, such as fatal familial insomnia (FFI) and familial Creutzfeldt-Jakob disease (fCJD), are associated with autosomal dominant mutations in the human prion protein gene

Indexed as

AnimalsAnimals, Genetically ModifiedBlotting, WesternCricetinaeDrosophila melanogasterEndopeptidase KHumansLocomotionMiceMicroscopy, ConfocalMutationNeurotoxinsPrion DiseasesPrion ProteinsTransgenesEndopeptidase KNeurotoxinsPrion ProteinsDrosophila melanogastergeneticneurotoxicityprionPrPSctransmissible

Identifiers

PMID28814578
PMCPMC5606059
OpenAlexW2748510072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.