ArticleThe Journal of experimental medicine2017
Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling.
Article in The Journal of experimental medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Runx-CBFβ regulates the development of tolerogenic Thetis cells.Nature immunology · 2026Article
- Metabolic adaption of mucosal macrophages: Is metabolism a driver of persistence across tissues?Mucosal immunology · 2023Review
- Downregulation of chemokine receptor 9 facilitates CD4Nature communications · 2023Article
- Nano drug delivery systems: a promising approach to scar prevention and treatment.Journal of nanobiotechnology · 2023Review
- BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207The Journal of investigative dermatology · 2022Article
- Niche rather than origin dysregulates mucosal Langerhans cells development in aged mice.Mucosal immunology · 2020Article
- The Roles of RUNX Family Proteins in Development of Immune Cells.Molecules and cells · 2020Review
- Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity.Nature communications · 2020Article
- Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming RorγtLife science alliance · 2020Article
- EXTL3-interacting endometriosis-specific serum factors induce colony formation of endometrial stromal cells.Scientific reports · 2019Article
- A wave of monocytes is recruited to replenish the long-term Langerhans cell network after immune injury.Science immunology · 2019Article
- Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors.The Journal of experimental medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mouse Langerhans cell (LC) network is established through the differentiation of embryonic LC precursors. BMP7 and TGFβ1 initiate cellular signaling that is essential for inducing LC differentiation and preserving LCs in a quiescent state, respectively. Here we show that loss of Cbfβ2, one of two RNA splice variants of the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.