Evidence map›Paper›PMID 28814545›Full record

ArticleScience translational medicine2017

Metabolic differentiation of early Lyme disease from southern tick-associated rash illness (STARI).

Claudia R Molins, Laura V Ashton, Gary P Wormser, Barbara G Andre, Ann M Hess, Mark J Delorey, Mark A Pilgard, Barbara J Johnson, Kristofor Webb, M Nurul Islam and 4 more

Abstract read
In one paragraph

Article in Science translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Lyme borreliosis.Nature reviews. Disease primers · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Insights From Omics in Lyme Disease.The Journal of infectious diseases · 2024
    Review
  7. Review
  8. Article
  9. Current Knowledge in Skin Metabolomics: Updates from Literature Review.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Metabolic Response in Patients With Post-treatment Lyme Disease Symptoms/Syndrome.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  12. Review
  13. Discovery and Surveillance of Tick-Borne Pathogens.Journal of medical entomology · 2021
    Article
  14. Article
  15. Laboratory Diagnosis of Lyme Borreliosis.Clinical microbiology reviews · 2021
    Review
  16. Lone Star Ticks (Delaware journal of public health · 2021
    Article
  17. Ticks: More Than Just a Pathogen Delivery Service.Frontiers in cellular and infection microbiology · 2021
    Article
  18. Lyme Disease in Humans.Current issues in molecular biology · 2021
    Article
  19. Article
  20. Emerging Tick-Borne Diseases.Clinical microbiology reviews · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Claudia R MolinsDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA.ORCID http://orcid.org/0000-0002-6083-4918
Laura V AshtonDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA.
Gary P WormserDivision of Infectious Diseases,Department of Medicine, New York Medical College, Valhalla, NY 10595, USA.
Barbara G AndreDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.ORCID http://orcid.org/0000-0002-4221-1979
Ann M HessDepartment of Statistics, Colorado State University, Fort Collins, CO 80523, USA.
Mark J DeloreyDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA.
Mark A PilgardDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA.
Barbara J JohnsonDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA.
Kristofor WebbDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.ORCID http://orcid.org/0000-0001-8111-9756
M Nurul IslamDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Adoracion Pegalajar-JuradoDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA.
Irida MollaDivision of Infectious Diseases,Department of Medicine, New York Medical College, Valhalla, NY 10595, USA.
Mollie W JewettDivision of Immunology and Pathogenesis, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32816, USA.ORCID http://orcid.org/0000-0003-3130-3795
John T BelisleDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA. john.belisle@colostate.edu.ORCID http://orcid.org/0000-0002-2539-2798

Funding

Determination of the genetic basis for B. burgdorferi mammalian infectivityR01AI099094 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI Mollie W Jewett · 2013 to 2026
$4.0M
Metabolic biomarkers and biosignatures for improved diagnosis of Lyme diseaseR33AI100228 · NIAID · COLORADO STATE UNIVERSITY · PI BELISLE, JOHN T · 2014 to 2016
$1.4M
Metabolic biomarkers and biosignatures for improved diagnosis of Lyme diseaseR21AI100228 · NIAID · COLORADO STATE UNIVERSITY · PI BELISLE, JOHN T · 2012 to 2013
$420k
NIAID NIH HHS R01 AI099094NIAID NIH HHS R21 AI100228NIAID NIH HHS R33 AI100228
6 · The paper itself

Abstract

Lyme disease, the most commonly reported vector-borne disease in the United States, results from infection with

Indexed as

AnimalsCase-Control StudiesComputer SimulationDiagnosis, DifferentialExanthemaFemaleGeographyHumansLyme DiseaseMaleMetabolic Networks and PathwaysMetabolomeMetabolomicsMiddle AgedTick Infestations

Identifiers

PMID28814545
PMCPMC5773101

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.