Evidence map›Paper›PMID 28814513›Full record

ArticleJournal of virology2017

Escape of Tick-Borne Flavivirus from 2'-

Ludek Eyer, Hirofumi Kondo, Darina Zouharova, Minato Hirano, James J Valdés, Memi Muto, Tomas Kastl, Shintaro Kobayashi, Jan Haviernik, Manabu Igarashi and 13 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Molecules (Basel, Switzerland) · 2024
    Review
  8. Tick-Borne Encephalitis (TBE): From Tick to Pathology.Journal of clinical medicine · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Viral RNA-Dependent RNA Polymerase Inhibitor 7-Deaza-2'-Antimicrobial agents and chemotherapy · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 8 institutions in 4 countries.

Ludek EyerDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Hirofumi KondoLaboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Darina ZouharovaDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Minato HiranoLaboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
James J ValdésDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Memi MutoLaboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Tomas KastlDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Shintaro KobayashiLaboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Jan HaviernikDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Manabu IgarashiResearch Center for Zoonosis Control, Hokkaido University, Sapporo, Japan.
Hiroaki KariwaLaboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Marketa VaculovicovaDepartment of Chemistry and Biochemistry, Mendel University in Brno, Brno, Czech Republic.
Jiri CernyDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Rene KizekCentral Laboratories, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic.
Andrea KrögerInstitute for Medical Microbiology, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Stefan LienenklausInstitute for Laboratory Animal Science, Hannover Medical School, Hannover, Germany.
Milan DejmekInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.
Radim NenckaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.
Martin PalusDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Jiri SalatDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic.
Erik De ClercqRega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Kentaro YoshiiLaboratory of Public Health, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Daniel RuzekDepartment of Virology, Veterinary Research Institute, Brno, Czech Republic ruzekd@paru.cas.cz.
Veterinary Research Institute · CZHokkaido University · JPCzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZCentral European Institute of Technology · CZMedizinische Hochschule Hannover · DEOtto-von-Guericke-Universität Magdeburg · DERega Institute for Medical Research · BEUniversity of Veterinary Sciences Brno · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tick-borne encephalitis virus (TBEV) causes a severe and potentially fatal neuroinfection in humans. Despite its high medical relevance, no specific antiviral therapy is currently available. Here we demonstrate that treatment with a nucleoside analog, 7-deaza-2'-

Indexed as

antiviral agentsantiviral therapyescape mutanttick-borne encephalitis virustick-borne pathogens

Identifiers

PMID28814513
PMCPMC5640847
OpenAlexW2750520736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.