ArticleHeart (British Cardiac Society)2018
Association of cardiovascular disease risk factors with coronary artery calcium volume versus density.
Article in Heart (British Cardiac Society), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Assessment of Subclinical Atherosclerosis in Asymptomatic People In Vivo: Measurements Suitable for Biomarker and Mendelian Randomization Studies.Arteriosclerosis, thrombosis, and vascular biology · 2024Pooled it
- Development and Validation of a Coronary Artery Calcium Volume and Density Score.Circulation. Cardiovascular imaging · 2026Article
- Bridging Prevention and Imaging: The Influence of Statins on CAC and CCTA Findings.Current atherosclerosis reports · 2025Review
- Association of Oral Anticoagulant Therapy with the Prevalence and Severity of Vascular Calcification among Patients with Atrial Fibrillation: A Cohort Study.ACS pharmacology & translational science · 2024Article
- Coronary artery calcification: concepts and clinical applications.Annals of medicine and surgery (2012) · 2024Review
- A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization.APL bioengineering · 2024Article
- Long-term all-cause death prediction by coronary, aortic, and valvular calcification in patients with acute ST-segment elevation myocardial infarction.BMC cardiovascular disorders · 2024Article
- Screening for Subclinical Atherosclerosis and the Prediction of Cardiovascular Events in People with Type 1 Diabetes.Journal of clinical medicine · 2024Review
- Structural and social determinants of health: The multi-ethnic study of atherosclerosis.PloS one · 2024Article
- Artificial Intelligence Empowered Nuclear Medicine and Molecular Imaging in Cardiology: A State-of-the-Art Review.Phenomics (Cham, Switzerland) · 2023Review
- Coronary calcium density in relation to coronary heart disease and cardiovascular disease in adults with diabetes or metabolic syndrome: the Multi-ethnic Study of Atherosclerosis (MESA).BMC cardiovascular disorders · 2022Article
- Muscular Strength and Carotid Intima-Media Thickness in Physically Fit Young Adults: The CHIEF Atherosclerosis Study.Journal of clinical medicine · 2022Article
- Evolving Role of Calcium Density in Coronary Artery Calcium Scoring and Atherosclerotic Cardiovascular Disease Risk.JACC. Cardiovascular imaging · 2022Review
- Coronary artery calcium incidence and changes using direct plaque measurements: The MASALA study.Atherosclerosis · 2022Article
- Cardiorespiratory Fitness and Carotid Intima-Media Thickness in Physically Active Young Adults: CHIEF Atherosclerosis Study.Journal of clinical medicine · 2022Article
- Subclinical cardiovascular disease and utility of coronary artery calcium score.International journal of cardiology. Heart & vasculature · 2021Review
- Association of calcium density in the thoracic aorta with risk factors and clinical events.European radiology · 2020Article
- Greater progression of coronary artery calcification is associated with clinically relevant cognitive impairment in type 1 diabetes.Atherosclerosis · 2019Article
- Risk of Atherosclerotic Cardiovascular Diseases in various Ethnicities of Pakistan.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 2 countries.
Funding
Abstract
objectivesRecently, the density score of coronary artery calcium (CAC) has been shown to be associated with a lower risk of cardiovascular disease (CVD) events at any level of CAC volume. Whether risk factors for CAC volume and CAC density are similar or distinct is unknown. We sought to evaluate the associations of CVD risk factors with CAC volume and CAC density scores.
methodsBaseline measurements from 6814 participants free of clinical CVD were collected for the Multi-Ethnic Study of Atherosclerosis. Participants with detectable CAC (n=3398) were evaluated for this study. Multivariable linear regression models were used to evaluate independent associations of CVD risk factors with CAC volume and CAC density scores.
resultsWhereas most CVD risk factors were associated with higher CAC volume scores, many risk factors were associated with
conclusionsIn a cohort free of clinical CVD, CVD risk factors are differentially associated with CAC volume and density scores, with many CVD risk factors
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.