ArticleEndocrine connections2017
Iodine excess exposure during pregnancy and lactation impairs maternal thyroid function in rats.
Article in Endocrine connections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Changes in Central Sensitivity to Thyroid Hormones vs. Urine Iodine during Pregnancy.Medical sciences (Basel, Switzerland) · 2024Article
- The Role of Thyroid Hormone Synthesis Gene-Related miRNAs Profiling in Structural and Functional Changes of The Thyroid Gland Induced by Excess Iodine.Biological trace element research · 2024Article
- Associations between urinary iodine concentration and the prevalence of metabolic disorders: a cross-sectional study.Frontiers in endocrinology · 2023Article
- Study on the Effect of Different Iodine Intake on Hippocampal Metabolism in Offspring Rats.Biological trace element research · 2022Article
- Mechanisms of Sodium/Iodide Symporter-Mediated Mammary Gland Iodine Compensation during Lactation.Nutrients · 2022Article
- The Role of Iodine for Thyroid Function in Lactating Women and Infants.Endocrine reviews · 2022Review
- SLC34A2 Up-regulation And SLC4A4 Down-regulation Correlates With Invasion, Metastasis, And The MAPK Signaling Pathway In Papillary Thyroid Carcinomas.Journal of Cancer · 2021Article
- The Transcriptomic Response of the Murine Thyroid Gland to Iodide Overload and the Role of the Nrf2 Antioxidant System.Antioxidants (Basel, Switzerland) · 2020Article
- Effects of repetitive Iodine thyroid blocking on the foetal brain and thyroid in rats: a systems biology approach.Scientific reports · 2020Article
- Variation of iodine status during pregnancy and its associations with thyroid function in women from Rio de Janeiro, Brazil.Public health nutrition · 2019Article
- Para-occupational exposure to pesticides, PON1 polymorphisms and hypothyroxinemia during the first half of pregnancy in women living in a Mexican floricultural area.Environmental health : a global access science source · 2019Article
- Maternal Exposure to Iodine Excess Throughout Pregnancy and Lactation Induces Hypothyroidism in Adult Male Rat Offspring.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adequate maternal iodine consumption during pregnancy and lactation guarantees normal thyroid hormones (TH) production, which is crucial to the development of the fetus. Indeed, iodine deficiency is clearly related to maternal hypothyroidism and deleterious effects in the fetal development. Conversely, the effects of iodine excess (IE) consumption on maternal thyroid function are still controversial. Therefore, this study aimed to investigate the impact of IE exposure during pregnancy and lactation periods on maternal hypothalamus-pituitary-thyroid axis. IE-exposed dams presented reduced serum TH concentration and increased serum thyrotropin (TSH) levels. Moreover, maternal IE exposure increased the hypothalamic expression of
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