ArticleAmerican journal of physiology. Renal physiology2017
Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice.
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Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
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Who cites it
43 citing papers in PubMed, 64 citations in OpenAlex.
- Loss of OXGR1 function uncouples intrarenal RAS activation from pendrin and αENaC regulation and blunts angiotensin II-induced hypertension.Frontiers in pharmacology · 2026Article
- Renal tubular (pro)renin receptor deletion exacerbates kidney injury inAmerican journal of physiology. Renal physiology · 2025Article
- Intercalated Cell ClC-K2 Channel Contributes to Systemic ClFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- (Pro)renin Receptor Blockade Prevents Increases in Systolic Blood Pressure, Sodium Retention, and αENaC Protein Expression in the Kidney of 2K1C Goldblatt Mice.International journal of molecular sciences · 2025Article
- GLUT1 and prorenin receptor mediate differential regulation of TGF-β and CTGF in renal inner medullary collecting duct cells during high glucose conditions.Biological research · 2024Article
- OXGR1-Dependent (Pro)Renin Receptor Upregulation in Collecting Ducts of the Clipped Kidney Contributes to NaInternational journal of molecular sciences · 2024Article
- Human soluble prorenin receptor expressed in mouse renal collecting duct shows sex-specific effect on cardiorenal function.American journal of physiology. Renal physiology · 2024Article
- Kidney Renin-Angiotensin System: Lost in a RAS Cascade.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Reactivity of renal and mesenteric resistance vessels to angiotensin II is mediated by NOXA1/NOX1 and superoxide signaling.American journal of physiology. Renal physiology · 2023Article
- Soluble (Pro)Renin Receptor in Hypertension.Nephron · 2023Review
- Sex differences in the renin-angiotensin-aldosterone system and its roles in hypertension, cardiovascular, and kidney diseases.Frontiers in cardiovascular medicine · 2023Review
- Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice.American journal of physiology. Renal physiology · 2023Article
- Potential of soluble (pro)renin receptor in kidney disease: can it go beyond a biomarker?American journal of physiology. Renal physiology · 2022Review
- Bile acids regulate the epithelial NaThe Journal of physiology · 2022Article
- Cell-Specific Actions of the Prostaglandin E-Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages.Journal of the American Heart Association · 2022Article
- Genetic Modifications to Alter Blood Pressure Level.Biomedicines · 2022Review
- Renal NOXA1/NOX1 Signaling Regulates Epithelial Sodium Channel and Sodium Retention in Angiotensin II-induced Hypertension.Antioxidants & redox signaling · 2022Article
- (Pro)renin Receptor Regulates Phosphate Homeostasis in RatsFrontiers in physiology · 2022Article
- Hormone-Dependent Regulation of Renin and Effects on Prorenin Receptor Signaling in the Collecting Duct.Current hypertension reviews · 2022Article
- Knockout of Nephron ATP6AP2 Impairs Proximal Tubule Function and Prevents High-Fat Diet-Induced Obesity in Male Mice.Endocrinology · 2021Article
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Authors and funding
13 authors at 6 institutions in 3 countries.
Minolfa C PrietoDepartment of Physiology, Tulane University School of Medicine, New Orleans, Louisiana; mprieto@tulane.edu.
Virginia ReverteDepartment of Physiology, Tulane University School of Medicine, New Orleans, Louisiana.
Mykola MamenkoUniversity of Texas Health Science Center at Houston, Houston Texas.ORCID http://orcid.org/0000-0001-8683-0715
Marta KuczeriszkaDepartment of Physiology, Tulane University School of Medicine, New Orleans, Louisiana.
Luciana C VeirasKeck School of Medicine of USC, Los Angeles, California.
Carla B RosalesDepartment of Physiology, Tulane University School of Medicine, New Orleans, Louisiana.
Matthew McLellanDepartment of Physiology, Tulane University School of Medicine, New Orleans, Louisiana.
Oliver GentileDepartment of Physiology, Tulane University School of Medicine, New Orleans, Louisiana.
V Behrana JensenVeterinary Medicine and Surgery, UT MD Anderson Cancer Center, Houston, Texas.
Atsuhiro IchiharaTokyo Women's Medical University, Department of Medicine II, Tokyo, Japan; and.
Alicia A McDonoughKeck School of Medicine of USC, Los Angeles, California.
Oleh M PochynyukUniversity of Texas Health Science Center at Houston, Houston Texas.
Alexis A GonzalezInstituto de Química, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Tulane University · USKeck Hospital of USC · USThe University of Texas Health Science Center at Houston · USPontificia Universidad Católica de Valparaíso · CLThe University of Texas MD Anderson Cancer Center · USTokyo Women's Medical University · JP
Funding
Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1MSodium transporter regulation during hypertensionR01DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AURELIE EDWARDS, Alicia A. McDonough · 2011 to 2026
$5.8MAldosterone-independent regulation of ENaC by systemic saltR01DK095029 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI POCHYNYUK, OLEH · 2012 to 2016
$1.6MNIDDK NIH HHS R01 DK083785NIDDK NIH HHS R01 DK095029NIGMS NIH HHS U54 GM104940
Abstract
Augmented intratubular angiotensin (ANG) II is a key determinant of enhanced distal Na
Indexed as
Angiotensin IIBlood PressureNatriuresisRenal EliminationAnimalsDisease Models, AnimalEpithelial Sodium ChannelsGenetic Predisposition to DiseaseHypertensionKidney Tubules, CollectingMice, Inbred C57BLMice, KnockoutPhenotypeProrenin ReceptorProteinuriaProton-Translocating ATPasesAngiotensin IIATP6AP2 protein, mouseEpithelial Sodium ChannelsProrenin ReceptorProton-Translocating ATPasesReceptors, Cell SurfaceReninScnn1a protein, mouseScnn1g protein, mouseSodiumSodium Chloride, Dietaryblood pressuredistal tubular Na+ transportproreninreninrenin-angiotensin system
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.