Evidence map›Paper›PMID 28813578›Full record

Observational studyInvestigative ophthalmology & visual science2017

Incomitance and Eye Dominance in Intermittent Exotropia.

Daniel L Adams, John R Economides, Jonathan C Horton

Abstract readObservational Study
In one paragraph

Observational study in Investigative ophthalmology & visual science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Inferior displacement of the lateral rectus muscle insertion in exotropia with mild V-pattern or vertical deviation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  3. Observational
  4. Eye Tracking in Optometry: A Systematic Review.Journal of eye movement research · 2023
    Article
  5. Article
  6. Bilateral Occlusion Reduces the Ocular Deviation in Intermittent Exotropia.Investigative ophthalmology & visual science · 2021
    Article
  7. Article
  8. Article
  9. Binocular discrepancy in lateral rectus muscle attachment in intermittent exotropia with eye dominance.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  10. Evaluation of dynamic stereopsis in intermittent exotropia patients.International journal of ophthalmology · 2019
    Article
  11. Normal Topography and Binocularity of the Superior Colliculus in Strabismus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Daniel L AdamsDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California, United States.
John R EconomidesDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California, United States.
Jonathan C HortonDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California, United States.

Funding

STRUCTURAL BASIS OF AMBLYOPIA AND STRABISMUSR01EY010217 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HORTON, JONATHAN C · 1993 to 2018
$8.5M
NEI NIH HHS R01 EY010217
6 · The paper itself

Abstract

Purpose: To determine if the deviation angle changes in subjects with intermittent exotropia as they alternate fixation between the right and left eye in primary gaze. Methods: In this prospective observational cohort study, 37 subjects with intermittent exotropia were tested for evidence of incomitance. The position of each eye was recorded with a video tracker during fixation on a small central target. A cover-uncover test was performed by occluding one eye with a shutter that passed infrared light, allowing continuous tracking of both eyes. The deviation angle was measured during periods of right eye and left eye fixation. Incomitance was assessed as a function of eye preference, fixation stability, and exotropia variability. Results: The mean exotropia was 18.2° ± 8.1°. A difference between right exotropia and left exotropia was detectable in 16/37 subjects. Allowing for potential tracking error, the incomitance had a mean amplitude of 1.7°. It was not related to a difference in accommodative effort, eye preference, fixation stability, or variability in deviation. Conclusions: Comitance is regarded as a feature that distinguishes strabismus from paralytic or restrictive processes. Unexpectedly, eye tracking during the cover-uncover test showed that incomitance is present in approximately 40% of subjects with intermittent exotropia. It averages 10% of the exotropia, and can equal up to 5°. When substantial, it may be worth considering when planning surgical correction.

Indexed as

AdolescentAdultAgedChildDominance, OcularExotropiaEye MovementsFemaleFixation, OcularHumansMaleMiddle AgedOculomotor MusclesProspective StudiesVision, Binocular

Identifiers

PMID28813578
PMCPMC5559177

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.