ArticlePloS one2017
Increased risk of tinnitus in patients with chronic kidney disease: A nationwide, population-based cohort study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Low Evidence for Tinnitus Risk Factors: A Systematic Review and Meta-analysis.Journal of the Association for Research in Otolaryngology : JARO · 2023Pooled it
- Association between hypertension status and severity and tinnitus: a cross-sectional analysis of the Fasa adult cohort study.BMJ open · 2026Article
- Assessment of Macular Choroidal Thickness via Enhanced Depth Imaging Optical Coherence Tomography in Patients With Chronic Tinnitus.Journal of ophthalmology · 2026Article
- Analysis of Auditory Function before and after a Single Session of Hemodialysis in Patients with Chronic Kidney Disease.International archives of otorhinolaryngology · 2025Article
- Association of Chronic Kidney Disease with Prior Tinnitus: A Case-Control Study.Journal of clinical medicine · 2022Article
- Associations between intake of dietary flavonoids and the 10-year incidence of tinnitus in older adults.European journal of nutrition · 2022Article
- Chronic kidney disease is associated with increased risk of sudden sensorineural hearing loss and Ménière's disease: a nationwide cohort study.Scientific reports · 2021Article
- Macrolide-associated ototoxicity: a cross-sectional and longitudinal study to assess the association of macrolide use with tinnitus and hearing loss.The Journal of antimicrobial chemotherapy · 2021Article
- Tinnitus and Neuropsychological Dysfunction in the Elderly: A Systematic Review on Possible Links.Journal of clinical medicine · 2021Review
- Investigation of the Impact of Endodontic Therapy on Survival among Dialysis Patients in Taiwan: A Nationwide Population-Based Cohort Study.International journal of environmental research and public health · 2021Article
- Otorhinolaryngological dysfunctions induced by chronic kidney disease in pre- and post-transplant stages.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Review
- Hormone replacement therapy decreases the risk of tinnitus in menopausal women: a nationwide study.Oncotarget · 2018Article
- Association Between Cannabis Use and Tinnitus: A Multi-Center Propensity-Score-Matched Cohort Study.OTO openArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tinnitus mostly results from central and peripheral auditory pathology. Chronic kidney disease (CKD) is a major risk factor for cerebrovascular disease. However, no studies have evaluated the association between tinnitus and CKD. The aim of this study is to investigate the risk of tinnitus in patients with CKD. This retrospective cohort study was conducted using Taiwan National Health Insurance Research Database from 2000 to 2010. We established a CKD group (n = 185,430) and a non-CKD comparison group (n = 556,290) to investigate the incidence of tinnitus. Cox proportional hazard regression analysis was used to evaluate the effects of CKD on tinnitus risk. The results showed CKD significantly increased the risk of tinnitus (adjusted hazard ratio, 3.02; 95% CI, 2.655-3.456, P<0.001). A subgroup analysis revealed the increase in risk of tinnitus is more in CKD patients with heart failure (adjusted hazard ratio, 9.975; 95% CI, 5.001-18.752) and diabetes mellitus (adjusted hazard ratio, 3.712; 95% CI, 2.856-5.007). Furthermore, compared to non-CKD patients, the risk of tinnitus was increased 4.586-fold (95% CI, 2.399-6.7) in CKD patients with dialysis and 2.461-fold (95% CI, 1.033-3.454) in CKD patients without dialysis. This study is the first to report that CKD is associated with an increased risk of tinnitus. Among CKD cohort, patients with dialysis are at a higher risk of tinnitus than those without dialysis.
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