Evidence map›Paper›PMID 28813018›Full record

ArticleInternational journal of molecular sciences2017

Biophysical and Computational Studies of the vCCI:vMIP-II Complex.

Anna F Nguyen, Nai-Wei Kuo, Laura J Showalter, Ricardo Ramos, Cynthia M Dupureur, Michael E Colvin, Patricia J LiWang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Regulation of Chemokine-Receptor Interactions and Functions.International journal of molecular sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna F NguyenDepartments of Molecular Cell Biology and Chemistry and Chemical Biology, and the Health Sciences Research Institute, University of California Merced 5200 North Lake Rd, Merced, CA 953402, USA. aankirskaia@ucmerced.edu.
Nai-Wei KuoDepartments of Molecular Cell Biology and Chemistry and Chemical Biology, and the Health Sciences Research Institute, University of California Merced 5200 North Lake Rd, Merced, CA 953402, USA. nicolekuo2010@gmail.com.
Laura J ShowalterDepartments of Molecular Cell Biology and Chemistry and Chemical Biology, and the Health Sciences Research Institute, University of California Merced 5200 North Lake Rd, Merced, CA 953402, USA. lshowalter@ucmerced.edu.
Ricardo RamosDepartments of Molecular Cell Biology and Chemistry and Chemical Biology, and the Health Sciences Research Institute, University of California Merced 5200 North Lake Rd, Merced, CA 953402, USA. rramos4@ucmerced.edu.
Cynthia M DupureurDepartment of Chemistry & Biochemistry, University of Missouri-St. Louis, St. Louis, MO 63121, USA. dupureurc@umsl.edu.
Michael E ColvinDepartments of Molecular Cell Biology and Chemistry and Chemical Biology, and the Health Sciences Research Institute, University of California Merced 5200 North Lake Rd, Merced, CA 953402, USA. mcolvin@ucmerced.edu.
Patricia J LiWangDepartments of Molecular Cell Biology and Chemistry and Chemical Biology, and the Health Sciences Research Institute, University of California Merced 5200 North Lake Rd, Merced, CA 953402, USA. pliwang@ucmerced.edu.

Funding

Silk-based Formulation for Microbicide DeliveryR01AI112011 · NIAID · UNIVERSITY OF CALIFORNIA, MERCED · PI LIWANG, PATRICIA J · 2014 to 2017
$2.3M
NIAID NIH HHS R01 AI112011
6 · The paper itself

Abstract

Certain viruses have the ability to subvert the mammalian immune response, including interference in the chemokine system. Poxviruses produce the chemokine binding protein vCCI (viral CC chemokine inhibitor; also called 35K), which tightly binds to CC chemokines. To facilitate the study of vCCI, we first provide a protocol to produce folded vCCI from

Indexed as

Fluorescence PolarizationMolecular Dynamics SimulationChemokine CXCL2Herpesvirus 8, HumanMultiprotein ComplexesProtein Structure, QuaternaryVaccinia virusViral ProteinsChemokine CXCL2Multiprotein ComplexesViral Proteins35Kanti-inflammationchemokine analogchemokine binding proteinMIP-1β/CCL4molecular dynamicsvCCIvMIP-II

Identifiers

PMID28813018
PMCPMC5578167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.