Observational studyTherapeutic advances in respiratory disease2017
Modifiable risk factors associated with bronchiolitis.
Observational study in Therapeutic advances in respiratory disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- The severity of the first occurrence of bronchiolitis increased the risk of developing asthma symptoms.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Occult Serious Bacterial Infections in Neonates and Infants Up to Three Months of Age with Bronchiolitis: Are Invasive Cultures Required?Antibiotics (Basel, Switzerland) · 2024Article
- Health effects associated with exposure to secondhand smoke: a Burden of Proof study.Nature medicine · 2024Article
- Reduced Serum Brain-Derived Neurotrophic Factor in Infants Affected by Severe Bronchiolitis.Current neuropharmacology · 2024Article
- Case-control study of exclusive breast feeding and severe bronchiolitis in the United States.Paediatric and perinatal epidemiology · 2023Article
- Association between prenatal and neonatal risk factors and development of bronchiolitis in early life.Asia Pacific allergy · 2023Article
- Parents Reaching Out to Parents: An Appreciative, Qualitative Evaluation of Stakeholder Experiences of the Parent Champions in the Community Project.Children (Basel, Switzerland) · 2022Article
- Respiratory syncytial virus-associated hospitalisation in children aged ≤5 years: a scoping review of literature from 2009 to 2021.ERJ open research · 2022Article
- Association of breastfeeding with tidal breathing analysis in infants with bronchiolitis.World journal of clinical pediatrics · 2021Article
- Feeding in the first six months of life is associated with the probability of having bronchiolitis: a cohort study in Spain.International breastfeeding journal · 2021Article
- Changes in children's respiratory morbidity and residential exposure factors over 25 years in Chongqing, China.Journal of thoracic disease · 2020Article
- Comparison of clinically related factors and treatment approaches in patients with acute bronchiolitis.Turk pediatri arsivi · 2020Article
- Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy.Italian journal of pediatrics · 2019Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe sought to clarify possibly modifiable risk factors related to pollution responsible for acute bronchiolitis in hospitalized infants.
methodsFor this observational study, we recruited 213 consecutive infants with bronchiolitis (cases: median age: 2 months; age range: 0.5-12 months; boys: 55.4%) and 213 children aged <3 years (controls: median age: 12 months; age range: 0.5-36 months; boys: 54.5%) with a negative medical history for lower respiratory tract diseases hospitalized at 'Sapienza' University Rome and IRCCS Bambino Gesù Hospital. Infants' parents completed a standardized 53-item questionnaire seeking information on social-demographic and clinical characteristics, indoor pollution, eating habits and outdoor air pollution. Multivariate logistic regression analyses were run to assess the independent effect of risk factors, accounting for confounders and effect modifiers.
resultsIn the 213 hospitalized infants the questionnaire identified the following risk factors for acute bronchiolitis: breastfeeding ⩾3 months (OR: 2.1, 95% confidence interval [CI]: 1.2-3.6), presence of older siblings (OR: 2.8, 95% CI: 1.7-4.7), ⩾4 cohabitants (OR: 1.5, 95% CI: 1.1-2.1), and using seed oil for cooking (OR: 1.7, 95% CI: 1.2-2.6). Having renovated their home in the past 12 months and concurrently being exposed daily to smoking, involving more than 11 cigarettes and two or more smoking cohabitants, were more frequent factors in cases than in controls ( p = 0.021 and 0.05), whereas self-estimated proximity to road and traffic was similar in the two groups.
conclusionsWe identified several risk factors for acute bronchiolitis related to indoor and outdoor pollution, including inhaling cooking oil fumes. Having this information would help public health authorities draw up effective preventive measures - for example, teach mothers to avoid handling their child when they have a cold and eliminate exposure to second-hand tobacco smoke.
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