Evidence map›Paper›PMID 28812446›Full record

ArticleThe journal of spinal cord medicine2018

Higher dietary intake of vitamin D may influence total cholesterol and carbohydrate profile independent of body composition in men with Chronic Spinal Cord Injury.

Christopher Beal, Ashraf Gorgey, Pamela Moore, Nathan Wong, Robert A Adler, David Gater

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of spinal cord medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Article
  5. The Role of Vitamins in Spinal Cord Injury: Mechanisms and Benefits.Oxidative medicine and cellular longevity · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Christopher Beala Spinal Cord Injury Service and Disorders , Hunter Holmes McGuire VA Medical Center , Richmond , Virginia , USA.
Ashraf Gorgeya Spinal Cord Injury Service and Disorders , Hunter Holmes McGuire VA Medical Center , Richmond , Virginia , USA.ORCID 0000-0002-9157-6034
Pamela Moorea Spinal Cord Injury Service and Disorders , Hunter Holmes McGuire VA Medical Center , Richmond , Virginia , USA.ORCID 0000-0002-3717-195X
Nathan Wonga Spinal Cord Injury Service and Disorders , Hunter Holmes McGuire VA Medical Center , Richmond , Virginia , USA.
Robert A Adlerc Endocrinology Service , Hunter Holmes McGuire VA Medical Center , Richmond , Virginia , USA.
David Gatere Department of Physical Medicine and Rehabilitation, Milton S. Hershey Medical Center , Penn State University , Hershey , Pennsylvania , USA.
Virginia Commonwealth University · USHunter Holmes McGuire VA Medical Center · USPenn State Milton S. Hershey Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designA case-control design.

objectivesTo determine the effects of dietary vitamin D intake on insulin sensitivity (Si), glucose effectiveness (Sg), and lipid profile in individuals with spinal cord injury (SCI).

methods20 male, paraplegic (T3-L1) with chronic (> one year) motor complete SCI (AIS A or B) were recruited. Three-day dietary records were analyzed for dietary vitamin D (calciferol), and participants were assigned to one of two groups, a high vitamin D intake group and a low vitamin D intake group based on the mid-point of vitamin D frequency distribution. Individuals in both groups were matched based on age, weight, time since injury and level of injury. Sg, Si and lipid profiles were measured of the two groups.

resultsThe high vitamin D group had an average intake of 5.33 ± 4.14 mcg compared to low vitamin D group, 0.74 ± 0.24 mcg. None of the 20 participants met the recommended guidelines for daily vitamin D intake. The higher vitamin D group had a significantly lower (P = 0.035) total cholesterol (148.00 ± 14.12 mg/dl) than the lower vitamin D group (171.80 ± 36.22 mg/dl). Vitamin D adjusted to total dietary intake was positively correlated to improvement in Si and Sg (P<0.05).

conclusionThe findings suggest that persons with SCI consume much less than the recommended guidelines for daily vitamin D intake. However, a higher dietary intake of vitamin D may influence total cholesterol and carbohydrate profile as demonstrated by a significant decrease in total cholesterol and improvement in glucose homeostasis independent of body composition changes after SCI.

Indexed as

Body CompositionAdultAgedBlood GlucoseCase-Control StudiesCholesterolDietary SupplementsHumansInsulin ResistanceMaleMiddle AgedRecommended Dietary AllowancesSpinal Cord InjuriesVitamin DVitaminsBlood GlucoseCholesterolVitamin DVitaminsBody compositionCarbohydrateCholesterolInsulin sensitivityLipid profileSpinal cord injuryVitamin D

Identifiers

PMID28812446
PMCPMC6055974
OpenAlexW2747341534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.